Highlight
– Gout is identified as an independent risk factor for ischemic stroke in patients with atrial fibrillation (AF).
– Urate-lowering therapy in patients with both gout and AF is associated with a significant reduction in stroke risk.
– Stroke risk stratification models for AF may benefit from incorporating gout status.
– The findings stem from a comprehensive nationwide cohort of 229,565 Finnish patients, enhancing the generalizability of results.
