Medxy AI – Page 2

Low-Yield or High-Value? Preoperative Cardiac Workup in Children With Very Severe OSA

By MedXY 06/18/2026

Preoperative cardiac testing in children with very severe OSA had low diagnostic yield and rarely changed management. Risk appeared highest in obese adolescents with AHI >50 events/hour.

General Surgery news Orthopedics

Postoperative Outcomes of Morel-Lavallée Injuries and Predictive Factors for Wound Complications

By MedXY 06/18/2026

A multicenter trauma study found that 20.1% of surgically treated Morel-Lavallée lesions developed wound complications. Pedestrian-versus-vehicle injury was the only independent predictor of postoperative problems.

Gastroenterology news Oncology

Immune Checkpoint Inhibitors Deliver Durable Responses in MSI-H Gastroesophageal Adenocarcinoma

By MedXY 06/18/2026

MSI-H/dMMR gastroesophageal adenocarcinoma showed high response rates to immune checkpoint inhibitors, including durable complete responses in locoregional disease that may support carefully selected nonoperative management.

Gastroenterology news Oncology

Checkpoint Blockade Delivers Deep, Durable Responses in MSI-H Gastroesophageal Adenocarcinoma

By MedXY 06/18/2026

This single-center cohort found high and durable checkpoint inhibitor responses in dMMR/MSI-H gastroesophageal adenocarcinoma, including complete responses in locoregional disease that may support carefully selected nonoperative management.

Diabetes & Endocrinology news Oncology

GLP-1 Receptor Agonists May Outperform Bariatric Surgery for Breast Cancer Outcomes in Obese Postmenopausal Women

By MedXY 06/18/2026

In a large TriNetX study, GLP-1 receptor agonists were associated with better overall survival and lower locoregional recurrence than bariatric surgery alone in obese postmenopausal women with stage 0-III breast cancer.

Hematology-Oncology news OB/GYN & Women’s Health

GLP-1 Receptor Agonists May Outperform Bariatric Surgery in Obese Postmenopausal Breast Cancer Patients, Study Suggests

By MedXY 06/18/2026

A large real-world study found GLP-1 receptor agonists were associated with better survival and lower locoregional recurrence than bariatric surgery in postmenopausal women with obesity and breast cancer.

news OB/GYN & Women’s Health Oncology

Prehabilitation During Neoadjuvant Chemotherapy May Improve Surgery Eligibility and Chemotherapy Delivery in Advanced Ovarian Cancer

By MedXY 06/18/2026

A matched-cohort study found that multimodal prehabilitation during neoadjuvant chemotherapy improved chemotherapy delivery and increased the chance of interval debulking surgery in advanced ovarian cancer, with the strongest benefits seen in patients aged 70 and older.

news OB/GYN & Women’s Health Pediatrics

When the Prenatal Ultrasound “Level” Does Not Match the Neurologic Reality: Mapping Anatomical-Motor Discordance in Open Spinal Dysraphism

By MedXY 06/18/2026

In 187 fetuses with open spinal dysraphism, prenatal motor level was more caudal than the anatomical level in 85% of cases, with larger gaps in myeloschisis and higher lesions.

news OB/GYN & Women’s Health Pediatrics

Why the Spinal Lesion Level on Prenatal Ultrasound Often Does Not Match Fetal Motor Function

By MedXY 06/18/2026

Prenatal ultrasound in open spinal dysraphism often underestimates functional level: in 85% of fetuses, motor level was more caudal than anatomy. Lesion type and height influenced the gap, with implications for counseling and fetal care planning.

news OB/GYN & Women’s Health

From Symptoms to Preferences: Q-Methodology Maps What Women With Chronic Pelvic Pain Want From Treatment

By MedXY 06/18/2026

A Q-methodology study translated chronic pelvic pain experiences into five patient preference profiles to better align counseling and treatment selection with what matters most to patients.

Infectious Diseases news OB/GYN & Women’s Health

Hantavirus in Pregnancy: Why Obstetricians Need a High Index of Suspicion

By MedXY 06/17/2026

Hantavirus infection in pregnancy is rare but potentially fatal. Obstetricians should suspect it after rodent or travel exposure, recognize rapid respiratory decline, and prioritize supportive critical care because no proven antiviral therapy exists.

Gastroenterology Internal Medicine news

Lower-Dose Vitamin E Works as Well as Higher Doses in MASLD, VEDS Trial Finds

By MedXY 06/17/2026

In adults with suspected MASH, 200 IU/day vitamin E lowered ALT as effectively as 400 IU/day and 800 IU/day over 24 weeks, with no short-term safety signal, supporting lower-dose use if vitamin E is chosen.

Gastroenterology news Oncology

SPP1-Positive Macrophages Shape Immunosuppression in Colorectal Cancer Lymph Nodes

By MedXY 06/17/2026

Single-cell profiling of colorectal cancer lymph nodes revealed an SPP1–CD44–NF-κB1 pathway that promotes CD137+ regulatory T-cell maturation and may be therapeutically targetable.

Gastroenterology news Public Health

Validated Early Detection Metrics Could Narrow Liver Fibrosis Screening Without Losing Clinical Signal

By MedXY 06/17/2026

A validation study suggests current liver fibrosis screening criteria are too broad. A refined risk-based approach reduced eligibility from 60–76% to 10–22% of adults while improving the yield of elevated liver stiffness and predicting future liver events.

news Pediatrics

New Consensus Maps the Future of Pediatric Stroke Rehabilitation in Australia and New Zealand

By MedXY 06/17/2026

A modified Delphi study reached regional consensus on the most important outcomes and measurement tools for pediatric stroke rehabilitation, highlighting practical ways to standardize care and research across Australasia.

Neurology news

A New Way to Measure Prodromal Synucleinopathy: What the PSRS Adds for RBD Clinical Trials

By MedXY 06/17/2026

The PSRS showed good-to-excellent reliability and moderate-to-strong construct validity in a large RBD cohort, supporting its use as a multidomain measure of prodromal synucleinopathy burden.

Neurology news Public Health

Brain Imaging Biomarkers and Cognitive Outcomes in a Multidomain Lifestyle Intervention: The POINTER Imaging Ancillary Study

By MedXY 06/17/2026

The POINTER Imaging study found no overall brain biomarker changes from a structured lifestyle intervention, but participants with lower baseline hippocampal volume showed greater cognitive benefit, suggesting imaging may help identify who responds best.

Diabetes & Endocrinology Nephrology news

Thyroid Hormones May Offer a New Therapeutic and Prognostic Angle in ADPKD

By MedXY 06/17/2026

Thyroid hormone signaling may influence ADPKD progression, with preclinical cyst suppression and patient biomarker associations suggesting prognostic and therapeutic potential.

Diabetes & Endocrinology news Public Health

Time-Restricted Eating vs Dietetic Guidance for Glycaemic Outcomes in Adults at Risk of Type 2 Diabetes

By MedXY 06/17/2026

Time-restricted eating performed similarly to individualized dietetic guidance for short-term HbA1c change in adults at risk of type 2 diabetes, but non-inferiority was not confirmed at 12 months. Benefits were small, and adverse events were minor.

Diabetes & Endocrinology news Oncology

Gestational Diabetes and Later Cancer Risk: Reassuring Overall Results, but a Kidney Cancer Signal Emerges

By MedXY 06/17/2026

A Danish registry study found no overall increase in selected cancers after gestational diabetes, but did observe a small absolute and relative increase in kidney cancer risk.

Low-Yield or High-Value? Preoperative Cardiac Workup in Children With Very Severe OSA

Postoperative Outcomes of Morel-Lavallée Injuries and Predictive Factors for Wound Complications

Immune Checkpoint Inhibitors Deliver Durable Responses in MSI-H Gastroesophageal Adenocarcinoma

Checkpoint Blockade Delivers Deep, Durable Responses in MSI-H Gastroesophageal Adenocarcinoma

GLP-1 Receptor Agonists May Outperform Bariatric Surgery for Breast Cancer Outcomes in Obese Postmenopausal Women

GLP-1 Receptor Agonists May Outperform Bariatric Surgery in Obese Postmenopausal Breast Cancer Patients, Study Suggests

Prehabilitation During Neoadjuvant Chemotherapy May Improve Surgery Eligibility and Chemotherapy Delivery in Advanced Ovarian Cancer

When the Prenatal Ultrasound “Level” Does Not Match the Neurologic Reality: Mapping Anatomical-Motor Discordance in Open Spinal Dysraphism

Why the Spinal Lesion Level on Prenatal Ultrasound Often Does Not Match Fetal Motor Function

From Symptoms to Preferences: Q-Methodology Maps What Women With Chronic Pelvic Pain Want From Treatment

Hantavirus in Pregnancy: Why Obstetricians Need a High Index of Suspicion

Lower-Dose Vitamin E Works as Well as Higher Doses in MASLD, VEDS Trial Finds

SPP1-Positive Macrophages Shape Immunosuppression in Colorectal Cancer Lymph Nodes

Validated Early Detection Metrics Could Narrow Liver Fibrosis Screening Without Losing Clinical Signal

New Consensus Maps the Future of Pediatric Stroke Rehabilitation in Australia and New Zealand

A New Way to Measure Prodromal Synucleinopathy: What the PSRS Adds for RBD Clinical Trials

Brain Imaging Biomarkers and Cognitive Outcomes in a Multidomain Lifestyle Intervention: The POINTER Imaging Ancillary Study

Thyroid Hormones May Offer a New Therapeutic and Prognostic Angle in ADPKD

Time-Restricted Eating vs Dietetic Guidance for Glycaemic Outcomes in Adults at Risk of Type 2 Diabetes

Gestational Diabetes and Later Cancer Risk: Reassuring Overall Results, but a Kidney Cancer Signal Emerges

Comparative 1-Year Outcomes of Semaglutide, Tirzepatide, and Sleeve Gastrectomy in Obese Adults with Type 2 Diabetes: Insights from Real-World Data

Unveiling the Phenotype of Unclassified Pulmonary Hypertension: A Hidden Spectrum of Early Heart Failure with Preserved Ejection Fraction

Biomarker, Functional Status, and Quality-of-Life Trajectories Before Modes of Death in Heart Failure: Post Hoc Analysis of the FINEARTS-HF Randomized Clinical Trial

Decoding SLC4A3 Mutations in Short QT Syndrome: Insights from hiPSC-Derived Cardiomyocytes into Ventricular Arrhythmia and Sudden Cardiac Death