Nephrology – Page 2

Predicting Two-Year Relapse Risk in ANCA-Associated Vasculitis: Insights from the PEXIVAS Trial

By MedXY 10/02/2026

A risk prediction model derived from the PEXIVAS trial estimates the 2-year relapse probability in ANCA-associated vasculitis, integrating clinical and laboratory factors to improve individualized patient management.

Infectious Diseases Nephrology news

Comparative Insights into Native and Allograft BK Polyomavirus Nephropathy: Clinical and Pathological Perspectives from a Matched Cohort Study

By MedXY 10/02/2026

This study elucidates the distinct clinical, pathological, and prognostic differences between native and allograft BK polyomavirus nephropathy, highlighting the severity and poorer outcomes associated with native-kidney BKPyVN and stressing the importance of early detection in high-risk patients.

Nephrology news

Optimizing Kidney Transplant Outcomes: Insights from a National Study on Dual Versus Single Kidney Transplantation

By MedXY 10/02/2026

This national matched cohort study highlights that dual kidney transplantation (DKT) offers improved graft and patient survival compared to single kidney transplantation (SKT) in select recipients, supporting its strategic use for hard-to-place donor kidneys in the U.S.

Diabetes & Endocrinology Nephrology news

Worsening Time in Range as a Predictor of Microvascular Complications in Type 1 Diabetes: Insights from a 5-Year Real-World Study

By MedXY 09/26/2026

A 5-year real-world cohort study reveals that declines in CGM-derived time in range correlate with increased microvascular complications in type 1 diabetes, offering prognostic value beyond HbA1c.

Cardiology Nephrology news

Ilofotase Alfa in Preventing Acute Kidney Injury Post-Cardiac Surgery: Insights from a Phase 2 Randomized Trial

By MedXY 09/24/2026

A phase 2 randomized trial found that ilofotase alfa did not significantly reduce kidney injury or improve outcomes in high-risk patients undergoing on-pump cardiac surgery, though it was safe and well tolerated.

Critical Care Nephrology news

Epidemiology and Outcomes of CRRT in Critically Ill Cirrhosis Patients: Insights from the HRS-HARMONY and CRRTnet Registries

By MedXY 09/24/2026

This study analyzes the epidemiology, treatment processes, and outcomes of critically ill cirrhosis patients undergoing continuous renal replacement therapy, highlighting high mortality rates, anticoagulation practices, and implications of CRRT dosing.

Nephrology news Respiratory

Impact of the 2023 Safety Net Policy on Kidney After Lung Transplantation: Early Changes in Transplant Practices and Outcomes

By MedXY 09/22/2026

Following the 2023 US safety net policy for kidney after lung transplantation, a shift from simultaneous lung-kidney transplants to early kidney transplantation post lung transplant was observed, with improved short-term outcomes and reduced delisting rates.

Cardiology Clinical Updates Nephrology news

Efficacy and Safety of Low-Dose Rivaroxaban in Advanced Chronic Kidney Disease with High Cardiovascular Risk: A Comprehensive Review

By MedXY 09/20/2026

Low-dose rivaroxaban failed to reduce cardiovascular events but increased major bleeding in advanced CKD patients at high cardiovascular risk, underscoring the need for cautious anticoagulant use.

Critical Care Nephrology news

Unlocking the Potential of Novel Biomarkers for Acute Kidney Injury in the Critically Ill: A Comprehensive Evidence Mapping

By MedXY 09/18/2026

This article reviews over 1100 studies on novel biomarkers for acute kidney injury (AKI) in critically ill patients, highlighting their predictive, diagnostic, and management roles while identifying gaps for future clinical implementation.

Internal Medicine Nephrology news

KDIGO 2026 on Anemia in CKD: Key Recommendations and Practical Guidance for Clinicians

By MedXY 09/18/2026

KDIGO 2026 updates anemia care in CKD: evidence-based thresholds for iron therapy, preference for IV iron on hemodialysis, ESA-first approach over HIF-PHIs, individualized Hb initiation, and an ESA maintenance upper Hb target <11.5 g/dL.

Diabetes & Endocrinology Nephrology news

Balancing Accuracy and Practicality: Should RAAS-Modifying Drugs Be Withdrawn in Primary Aldosteronism Diagnosis?

By MedXY 09/15/2026

This article examines the debate on whether RAAS-modifying antihypertensives should be stopped before testing for primary aldosteronism, weighing diagnostic accuracy against patient safety and feasibility.

Diabetes & Endocrinology Nephrology news

Advancing SGLT Inhibitor Use for Heart and Kidney Protection in Type 1 Diabetes: Opportunities and Challenges

By MedXY 09/14/2026

This article reviews expert perspectives on the efficacy and safety of SGLT inhibitors for cardiovascular and renal disease in type 1 diabetes, outlines translational insights from type 2 diabetes data, and proposes a roadmap for regulatory approval and clinical implementation focusing on surrogate endpoints and diabetic ketoacidosis risk mitigation.

Internal Medicine Nephrology news

Reevaluating Calcineurin Inhibitor Use in Identical Twin Kidney Transplants: Are We Overmedicating?

By MedXY 09/04/2026

Despite identical immunogenetic makeup, half of kidney transplant recipients from identical twins remain on calcineurin inhibitors, with no demonstrable benefit in rejection reduction or graft survival over 25 years, calling for critical reassessment of immunosuppressive practices in this unique cohort.

Cardiology Nephrology news

Finerenone in Hypertensive Non-Diabetic Chronic Kidney Disease: Evidence from the FIND-CKD Subgroup Analysis

By MedXY 09/02/2026

Finerenone significantly slows kidney function decline and reduces cardiovascular risk in hypertensive non-diabetic CKD patients, with manageable safety profiles, supporting its therapeutic role beyond diabetes.

Infectious Diseases Nephrology news

Efficacy and Outcomes of Short-Course Perioperative Antiviral Prophylaxis in Hepatitis C Viremic Donor Kidney Transplantation

By MedXY 08/20/2026

A 7-day perioperative sofosbuvir/velpatasvir prophylaxis in HCV-positive donor to HCV-negative recipient kidney transplants demonstrated sustained virologic response in over 92% of cases, with favorable 1-year graft survival and function.

Nephrology news Respiratory

Advancing Perioperative Risk Stratification: Predicting Acute Kidney Injury Following Lung Transplantation

By MedXY 08/20/2026

Comprehensive pre- and early postoperative models predict acute kidney injury and need for renal replacement after lung transplantation, improving risk stratification and enabling targeted nephroprotection.

Gastroenterology Nephrology news

Ciliogenic Pancreatopathy: A Novel Link Between Ciliopathies and Exocrine Pancreatic Disease

By MedXY 08/19/2026

Researchers unveil ciliogenic pancreatopathy, a new pancreatic disease connected to ciliary gene mutations, highlighting its clinical significance in patients with syndromic ciliopathies and kidney dysfunction.

Cardiology Nephrology news

Finerenone Efficacy in Cardio-Kidney-Metabolic Syndrome Patients With or Without History of Cancer: Insights from the FINE-HEART Analysis

By MedXY 08/19/2026

Finerenone reduces mortality, cardiovascular, and kidney complications in cardio-kidney-metabolic syndrome patients regardless of cancer history, while patients with cancer experience greater disease burden and adverse events.

Critical Care Nephrology news

Elevated Preoperative Serum Renin Predicts Vasopressor Need and Acute Kidney Injury in Liver Transplant Patients

By MedXY 08/17/2026

Pre-liver transplantation elevated serum renin levels correlate with increased intraoperative vasopressor use and postoperative acute kidney injury, suggesting its potential as a predictive biomarker for perioperative management and renal risk stratification.

Nephrology news Rheumatology

Decoding Fibrosis in Lupus Nephritis: Distinct Macrophage-Fibroblast Interactions Fuel Renal Damage

By MedXY 08/17/2026

Spatially distinct macrophage subsets interact with heterogeneous myofibroblast populations in lupus nephritis, driving maladaptive fibrosis and chronic kidney injury. Identifying these fibroinflammatory circuits offers promising targets for therapy to prevent renal decline.