Pathology & Lab Medicine/Bệnh học – Page 3

Safety of Biopsy in Pheochromocytoma and Paraganglioma: What a Global Study Found

By MedXY 05/15/2026

This international study found that biopsy of pheochromocytoma and paraganglioma had low mortality and low serious complication rates, suggesting biopsy may be reasonable in carefully selected patients with expert management.

Hematology-Oncology news Pathology & Lab Medicine/Bệnh học

Early ctDNA MRD After Two Cycles Identifies Distinct Relapse Risk Groups in Advanced Hodgkin Lymphoma

By MedXY 05/14/2026

In the GHSG HD21 trial, a validated ctDNA assay showed that MRD positivity after two treatment cycles strongly predicted inferior progression-free survival and improved early risk stratification, especially when combined with interim PET.

Cardiology news Pathology & Lab Medicine/Bệnh học

Why the cTnI/cTnT Ratio May Matter: A New Signal for Distinguishing Acute Necrotic From Chronic Myocardial Injury

By MedXY 05/12/2026

A large multicohort and experimental study suggests the cTnI/cTnT ratio is biologically informative, separates acute from chronic myocardial injury, and modestly improves type 1 versus type 2 MI discrimination.

Hematology-Oncology news Pathology & Lab Medicine/Bệnh học

TP53 Multihit Does Not Fully Erase the Prognostic Advantage of Isolated del(5q) in Myelodysplastic Neoplasms

By MedXY 05/09/2026

A multicenter retrospective study suggests that MDS with isolated del(5q) and TP53 multihit alterations has substantially better survival than other low-blast TP53-multihit MDS, challenging how this subgroup should be classified.

Gastroenterology news Pathology & Lab Medicine/Bệnh học

A Simple Five-Variable Index Helps Identify Excess Alcohol Use in Steatotic Liver Disease When PEth Testing Is Not Readily Available

By MedXY 05/07/2026

A new five-component biomarker panel, MAPI, showed consistent AUROC performance of about 0.75 for detecting MetALD-ALD and may help triage confirmatory PEth testing in steatotic liver disease.

Hematology-Oncology news Pathology & Lab Medicine/Bệnh học

MRD Does Not Consistently Predict PFS Across Modern CLL Trials: Why Surrogacy Depends on Therapy, Duration, and Sample Source

By MedXY 05/04/2026

A large meta-analysis shows MRD strongly predicts outcomes for individual patients with CLL, but is an inconsistent trial-level surrogate for progression-free survival, particularly with BTK inhibitor and venetoclax-based regimens.

Diabetes & Endocrinology news Pathology & Lab Medicine/Bệnh học

Urinary Free Cortisol Thresholds Sharpen the Differential Diagnosis of ACTH-Dependent Cushing’s Syndrome

By MedXY 05/03/2026

A Spanish multicenter validation study shows that urinary free cortisol expressed as multiples of the upper limit of normal can meaningfully stratify the likelihood of ectopic ACTH secretion versus Cushing’s disease.