Highlight
- Late-onset fetal growth impairment in dichorionic twins shows variable placental pathology risk depending on ultrasound phenotype.
- Singleton versus twin-specific growth charts yield differing associations between growth discordance, small-for-gestational-age status, and placental pathology.
- A novel three-tier risk categorization framework is proposed to stratify placental dysfunction likelihood by ultrasound-defined growth phenotypes.
- Findings provide a path for future clinical trials and guideline development tailored to managing twin pregnancies complicated by growth restriction.
Study Background
