COPD 肺部远程康复模式的技术与临床可行性：一项全面综述
Posted inClinical Updates news Rehabilitation Medicine Respiratory

Technical and Clinical Feasibility of a Pulmonary Telerehabilitation Model for People with COPD: A Comprehensive Review

This review synthesizes evidence on the feasibility, acceptance, and clinical outcomes of pulmonary telerehabilitation models in COPD, highlighting technical reliability, patient adherence, and clinical benefits from recent trials, including the novel HBPR application study (NCT05314686).
Posted innews OB/GYN & Women's Health Oncology

Expanding the Genetic Landscape in Ovarian Carcinoma: Insights from the PERSONA-Ovary Trial on Germline and Somatic Testing

The PERSONA-Ovary trial demonstrates the feasibility and clinical value of unselected germline multigene panel testing alongside somatic BRCA analysis in ovarian carcinoma, revealing a 29.7% pathogenic variant prevalence and optimal testing strategies for integrating genetics into routine care.
每8周一次长效注射卡博特韦-利匹韦林用于撒哈拉以南非洲HIV感染青少年：来自LATA试验及当代证据的启示
Posted inClinical Updates HIV/AIDS Infectious Diseases news

Long-Acting Injectable Cabotegravir-Rilpivirine Every 8 Weeks for Adolescents with HIV in Sub-Saharan Africa: Evidence from the LATA Trial and Contemporary Context

The LATA trial demonstrates that long-acting injectable cabotegravir-rilpivirine given every 8 weeks is superior to daily oral ART for maintaining virological suppression in adolescents with HIV in sub-Saharan Africa, with a favorable safety and acceptability profile, heralding a transformative option for this vulnerable population.
系统性硬化症中表型特异性的嵌合性染色体异常：对疾病亚型与临床结局的启示
Posted inHematology-Oncology news Rheumatology

Phenotype-Specific Mosaic Chromosomal Alterations in Systemic Sclerosis: Implications for Disease Subtypes and Clinical Outcomes

This article explores the differential associations of mosaic chromosomal alterations (mCAs), especially chromosomal loss and mosaic loss of the X chromosome, with systemic sclerosis and its subtypes, revealing phenotype-specific genetic contributions that may influence clinical manifestations and disease onset.