Medxy AI – Page 18

腎細胞癌の下大静脈血栓摘除術前に行う定位放射線焼灼療法：新たな第2相エビデンスの総括

Neoadjuvant Stereotactic Ablative Radiotherapy Prior to Inferior Vena Cava Thrombectomy in Renal Cell Carcinoma: A Synthesis of Emerging Phase 2 Evidence

By MedXY 10/20/2026

This review synthesizes phase 2 trial data supporting neoadjuvant stereotactic ablative radiotherapy for RCC with IVC tumor thrombus, highlighting improved recurrence-free survival, acceptable safety, and biomarker insights that underscore its potential as a novel preoperative strategy.

news Orthopedics Rehabilitation Medicine

Swimming Plus Education: Short-Term Benefits for Chronic Low Back Pain Management

By MedXY 10/20/2026

A randomized trial found that individualized swimming combined with education improves disability in chronic low back pain patients more than education alone, with benefits evident at 8 weeks but not sustained at 1 year.

news Nursing & care Public Health

Harnessing Patient-Centered Outcomes Data for Enhanced Rehabilitation Care and Reciprocal Learning

By MedXY 10/20/2026

This article explores the strategic use of patient-centered outcomes data to foster continuous learning and improve rehabilitation care at both individual and system levels, addressing challenges and proposing solutions for effective implementation.

Dentistry news Radiology

Intraoral Ultrasonography for Mid-Buccal Probing Depth Assessment: A Proof-of-Concept Clinical Agreement Study

By MedXY 10/20/2026

This study evaluates the accuracy and reliability of intraoral ultrasonography to measure gingival sulcus depth compared to traditional clinical probing, demonstrating high agreement and potential as a non-invasive diagnostic tool in dental practice.

Allergy & Immunology Gastroenterology news

Phase 2 Trial of Icotrokinra for Patients with Ulcerative Colitis

By MedXY 10/20/2026

This phase 2b trial demonstrates that oral icotrokinra, targeting the interleukin-23 receptor, significantly improves clinical outcomes in moderate to severe ulcerative colitis compared to placebo.

Gastroenterology Infectious Diseases news

Dynamic Immune Modulation by Pegylated Interferon-Alpha Post-NUC Withdrawal in Chronic Hepatitis B

By MedXY 10/19/2026

Pegylated interferon-alpha after nucleos(t)ide analog withdrawal induces coordinated expansion of regulatory B cells and contraction of HBV-specific T cells, impacting viral control and hepatic inflammation in HBeAg-negative chronic hepatitis B.

Neurology news

Epilepsy as a Significant Risk Factor for Young-Onset Dementia: Insights from Nationwide Studies in France and Sweden

By MedXY 10/19/2026

Nationwide analyses show that epilepsy markedly increases the risk of young-onset dementia (YOD) before age 65, with persistent associations even years after epilepsy diagnosis, underscoring the need for YOD risk assessment in epilepsy care.

HRS-7535：为二甲双胍与SGLT2抑制剂控制不佳的2型糖尿病带来新希望的口服GLP-1受体激动剂

Diabetes & Endocrinology news

HRS-7535: A Promising Oral GLP-1 Receptor Agonist for Type 2 Diabetes Uncontrolled by Metformin and SGLT2 Inhibitors

By MedXY 10/19/2026

This Phase II trial demonstrates that HRS-7535, an oral small-molecule GLP-1 receptor agonist, significantly improves glycaemic control and is well-tolerated in type 2 diabetes patients inadequately controlled with metformin and SGLT2 inhibitors.

心原性ショックにおける一時的機械的循環補助：2026年EAPCI–ACVCコンセンサスの重要推奨

Cardiology Critical Care news

Temporary Mechanical Circulatory Support in Cardiogenic Shock: Key Recommendations from the 2026 EAPCI–ACVC Consensus

By MedXY 10/19/2026

The 2026 EAPCI–ACVC consensus refines use of temporary mechanical circulatory support in acute myocardial infarction with cardiogenic shock, emphasizing phenotype-driven device selection, SCAI/SHARC staging, multidisciplinary shock teams and regionalized systems to improve outcomes.

Nephrology news Respiratory

Physical Activity and Organ Health After COVID-19: Insights from a Survivor Cohort Study

By MedXY 10/19/2026

This study explores how physical activity influences lung and kidney function in COVID-19 survivors, showing active survivors had better lung outcomes but no significant kidney benefits, highlighting the importance of tailored rehabilitation.

Dentistry news Public Health

Behind Hospital Doors: How Inpatients Spend Their Days in Acute and Rehabilitation Settings

By MedXY 10/19/2026

A behavioural mapping study reveals inpatient inactivity and isolation are common across acute and rehabilitation wards, highlighting the need for systemic changes to hospital routines and environments to boost physical, cognitive, and social participation.

Dentistry Internal Medicine news

Impact of Acid Type on the Efficacy of Experimental Fluoride Gels in Protecting Enamel from Erosion

By MedXY 10/19/2026

This study demonstrates that experimental fluoride gels reduce enamel mineral loss from citric acid erosion but not hydrochloric acid, highlighting acid type as a critical factor in designing effective anti-erosive dental treatments.

急性低酸素性呼吸不全に対するイソフルラン吸入鎮静：SAVE-ICUランダム化臨床試験から得られた知見

Clinical Updates Critical Care news Respiratory

Isoflurane-Based Inhaled Sedation for Acute Hypoxemic Respiratory Failure: Insights from the SAVE-ICU Randomized Clinical Trial

By MedXY 10/19/2026

This review critically examines the SAVE-ICU trial assessing isoflurane inhaled sedation versus intravenous sedation in mechanically ventilated adults with acute hypoxemic respiratory failure, highlighting implications for clinical practice and future research needs.

Clinical Updates Critical Care news Pediatrics

Evaluation of a Commercial Pediatric Sepsis Early Detection Alert in Emergency Departments: Efficacy, Equity, and Clinical Implications

By MedXY 10/19/2026

This review synthesizes evidence evaluating the Epic Pediatric Sepsis Early Detection Model (PESM), highlighting its low sensitivity for early sepsis identification, disparities in performance across demographics, and implications for clinical practice and future screening tool development.

news Rheumatology

A Novel Weighted Flare Score Enhances Prediction of Organ Damage in Systemic Lupus Erythematosus

By MedXY 10/19/2026

A newly developed weighted flare scoring system in SLE accurately predicts organ damage accumulation, outperforming traditional flare classifications and informing treat-to-target strategies.

Critical Care news Respiratory

Impact of Prioritization on Severe Primary Graft Dysfunction After Lung Transplantation: Disentangling Risk Factors and Outcomes

By MedXY 10/19/2026

Prioritized lung transplant recipients exhibit higher severe PGD rates and mortality, yet prioritization itself is not an independent PGD predictor; pre-transplant ECMO is the primary risk factor.

Dermatology news Oncology

Cancer Risks in Lichen Planus: Implications from a Nationwide Danish Cohort Study

By MedXY 10/19/2026

Lichen planus is linked to increased risks of oral and genital cancers, with risks correlating to lesion sites. Despite low absolute risks, vigilant cancer surveillance in LP patients is warranted.

Belotero Intense 联合利多卡因用于唇部增大：多中心随机研究证实其安全性与有效性

Dermatology news Plastic Surgery

Evaluating Belotero Intense with Lidocaine for Lip Augmentation: A Multicenter Randomized Study Demonstrates Safety and Efficacy

By MedXY 10/19/2026

This multicenter randomized study confirms that Belotero Intense with lidocaine is a safe and effective hyaluronic acid filler for lip augmentation, showing noninferiority to Restylane Silk and sustained improvement up to 48 weeks.

Chất chủ vận thụ thể GLP-1 và kết cục chăm sóc cấp tính tâm thần ở bệnh nhân tâm thần phân liệt kèm đái tháo đường týp 2: Góc nhìn từ dữ liệu EHR trong thực hành lâm sàng thực tế

Clinical Updates Diabetes & Endocrinology news Psychiatry

GLP-1 Receptor Agonists and Psychiatric Acute-Care Outcomes in Schizophrenia with Type 2 Diabetes: Insights from Real-World EHR Data

By MedXY 10/19/2026

This review synthesizes evidence on GLP-1 receptor agonist initiation impacting psychiatric hospitalisation and emergency visits in adults with schizophrenia and type 2 diabetes, highlighting metabolic and psychiatric interplay and therapeutic implications.

Critical Care Nephrology news

Reevaluating Oliguria Thresholds in Critical Care: Implications for AKI, CKD, and Mortality Risk

By MedXY 10/19/2026

New evidence suggests lower urine output thresholds than current standards better predict acute kidney injury, chronic kidney disease, and mortality in critically ill patients, urging redefinition of oliguria parameters in AKI diagnostics.

Neoadjuvant Stereotactic Ablative Radiotherapy Prior to Inferior Vena Cava Thrombectomy in Renal Cell Carcinoma: A Synthesis of Emerging Phase 2 Evidence

Swimming Plus Education: Short-Term Benefits for Chronic Low Back Pain Management

Harnessing Patient-Centered Outcomes Data for Enhanced Rehabilitation Care and Reciprocal Learning

Intraoral Ultrasonography for Mid-Buccal Probing Depth Assessment: A Proof-of-Concept Clinical Agreement Study

Phase 2 Trial of Icotrokinra for Patients with Ulcerative Colitis

Dynamic Immune Modulation by Pegylated Interferon-Alpha Post-NUC Withdrawal in Chronic Hepatitis B

Epilepsy as a Significant Risk Factor for Young-Onset Dementia: Insights from Nationwide Studies in France and Sweden

HRS-7535: A Promising Oral GLP-1 Receptor Agonist for Type 2 Diabetes Uncontrolled by Metformin and SGLT2 Inhibitors

Temporary Mechanical Circulatory Support in Cardiogenic Shock: Key Recommendations from the 2026 EAPCI–ACVC Consensus

Physical Activity and Organ Health After COVID-19: Insights from a Survivor Cohort Study

Impact of Acid Type on the Efficacy of Experimental Fluoride Gels in Protecting Enamel from Erosion

Isoflurane-Based Inhaled Sedation for Acute Hypoxemic Respiratory Failure: Insights from the SAVE-ICU Randomized Clinical Trial

Evaluation of a Commercial Pediatric Sepsis Early Detection Alert in Emergency Departments: Efficacy, Equity, and Clinical Implications

A Novel Weighted Flare Score Enhances Prediction of Organ Damage in Systemic Lupus Erythematosus

Impact of Prioritization on Severe Primary Graft Dysfunction After Lung Transplantation: Disentangling Risk Factors and Outcomes

Cancer Risks in Lichen Planus: Implications from a Nationwide Danish Cohort Study

Evaluating Belotero Intense with Lidocaine for Lip Augmentation: A Multicenter Randomized Study Demonstrates Safety and Efficacy

GLP-1 Receptor Agonists and Psychiatric Acute-Care Outcomes in Schizophrenia with Type 2 Diabetes: Insights from Real-World EHR Data

Reevaluating Oliguria Thresholds in Critical Care: Implications for AKI, CKD, and Mortality Risk

Exercise as a Cognitive Buffer in Midlife Women: Insights into Domain-Specific Effects and Modality Differences

Empowering Safer Mobility Behaviors to Prevent Falls in Parkinson’s Disease: Insights from Clinicians and Researchers

Eating Difficulty as a Marker for Broader Functional Vulnerability and Cognitive Decline in Older Adults: Insights from Four Large Ageing Cohorts

Izalontamab Brengitecan Shows Promising Efficacy Over Platinum Chemotherapy in EGFR-Mutated NSCLC Post-Third-Generation EGFR TKI Progression