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Mortality

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Incidence, Outcomes, and Risk Factors for Mortality in Patients With Sepsis in South Korea: Insights From a Nationwide Cohort Study and Related Evidence
Posted inClinical Updates news

Incidence, Outcomes, and Risk Factors for Mortality in Patients With Sepsis in South Korea: Insights From a Nationwide Cohort Study and Related Evidence

Posted by By MedXY 08/17/2026
This review synthesizes nationwide epidemiological trends of sepsis in South Korea from 2011 to 2022, elucidating incidence increases, declining in-hospital mortality, and key clinical and socioeconomic mortality determinants alongside relevant complementary studies.
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Timing Matters: Early Insulin Therapy Reduces Mortality in ICU Patients with Moderate Hyperglycemia
Posted inCritical Care Diabetes & Endocrinology news

Timing Matters: Early Insulin Therapy Reduces Mortality in ICU Patients with Moderate Hyperglycemia

Posted by By MedXY 08/17/2026
Early initiation of insulin within two hours for moderate hyperglycemia in ICU patients significantly lowers 30-day mortality compared to delayed or no insulin therapy. This target trial emulation highlights the potential clinical benefit of prompt insulin treatment timing in critical care.
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Medicaid Expansion and Reduced 1-Year Mortality in Young Adults Initiating Dialysis: A Comprehensive Review
Posted inClinical Updates Nephrology news Public Health

Medicaid Expansion and Reduced 1-Year Mortality in Young Adults Initiating Dialysis: A Comprehensive Review

Posted by By MedXY 08/17/2026
This review synthesizes evidence showing that Medicaid expansion under the Affordable Care Act significantly reduced 1-year mortality among young adults starting dialysis by improving insurance coverage and access to nephrology care.
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Net Ultrafiltration Rate and Mortality in Critically Ill CRRT Patients: The Crucial Role of Fluid Balance
Posted inCritical Care Nephrology news

Net Ultrafiltration Rate and Mortality in Critically Ill CRRT Patients: The Crucial Role of Fluid Balance

Posted by By MedXY 08/16/2026
A multicenter cohort study shows that in critically ill patients undergoing continuous renal replacement therapy, mortality is more closely associated with fluid balance changes than net ultrafiltration rate, emphasizing patient-specific fluid balance targets in care.
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Unraveling the Mortality Benefits of Beta-Blockers in COPD Patients with Cardiovascular Disease: Influence of LABA Co-therapy
Posted inCardiology news Respiratory

Unraveling the Mortality Benefits of Beta-Blockers in COPD Patients with Cardiovascular Disease: Influence of LABA Co-therapy

Posted by By MedXY 08/12/2026
A large UK cohort study reveals that beta-blockers reduce mortality in COPD patients with heart failure or ischemic heart disease, but concurrent long-acting beta-agonists may attenuate this benefit.
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Evaluating the Impact of a Prehospital 1-Hour Resuscitation Bundle on Septic Shock Mortality: Insights from the SAMU Save Sepsis Study
Posted inAllergy & Immunology Critical Care Emergency Medicine news

Evaluating the Impact of a Prehospital 1-Hour Resuscitation Bundle on Septic Shock Mortality: Insights from the SAMU Save Sepsis Study

Posted by By MedXY 08/11/2026
A multicenter randomized trial found that initiating a 1-hour resuscitation bundle including early antibiotics, fluids, vasopressors, and hydrocortisone in the prehospital setting did not significantly reduce 28-day mortality in adults with septic shock.
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Evaluating the Impact of a 1-Hour Prehospital Resuscitation Bundle on Septic Shock Outcomes
Posted inCritical Care Emergency Medicine news

Evaluating the Impact of a 1-Hour Prehospital Resuscitation Bundle on Septic Shock Outcomes

Posted by By MedXY 08/11/2026
A multicenter study investigated whether initiating a 1-hour resuscitation bundle—including antibiotics, fluids, vasopressors, and hydrocortisone—in the prehospital setting influences 28-day mortality in septic shock, finding no significant mortality benefit.
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Decoding the U-Shaped Relationship Between Left Ventricular Size and Mortality in Heart Failure Patients
Posted inCardiology news

Decoding the U-Shaped Relationship Between Left Ventricular Size and Mortality in Heart Failure Patients

Posted by By MedXY 08/07/2026
A large Chinese cohort study reveals a U-shaped association between left ventricular end-diastolic diameter and mortality in heart failure, highlighting both small and large ventricular sizes as independent risk factors.
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H3.1 Nucleosomes as Predictive Biomarkers for Renal Replacement Therapy and Mortality in Sepsis: Insights from the SISPCT Trial
Posted inCritical Care Nephrology news

H3.1 Nucleosomes as Predictive Biomarkers for Renal Replacement Therapy and Mortality in Sepsis: Insights from the SISPCT Trial

Posted by By MedXY 08/07/2026
Elevated plasma levels of H3.1 nucleosomes at ICU admission correlate with increased mortality and acute kidney injury requiring renal replacement therapy in sepsis, highlighting their potential as prognostic biomarkers.
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Reevaluating Acute Treatment Strategies for Spontaneous Spinal Cord Infarction: Insights from a Propensity Score-Matched Study
Posted inNeurology news

Reevaluating Acute Treatment Strategies for Spontaneous Spinal Cord Infarction: Insights from a Propensity Score-Matched Study

Posted by By MedXY 08/04/2026
This retrospective analysis reveals that standard antiplatelet therapy may reduce mortality compared to thrombolysis in acute spontaneous spinal cord infarction, highlighting the need for cautious therapeutic decisions pending stronger evidence.
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Validating VasCog-2-WSO Criteria: Early MRI Detection of Vascular Cognitive Impairment and Mortality Risk in Stroke- and Dementia-Free Adults
Posted inCardiology Neurology news

Validating VasCog-2-WSO Criteria: Early MRI Detection of Vascular Cognitive Impairment and Mortality Risk in Stroke- and Dementia-Free Adults

Posted by By MedXY 08/04/2026
The VasCog-2-WSO criteria effectively detect MRI-defined vascular cognitive impairment in asymptomatic adults, correlating with increased cardiovascular risk and mortality, highlighting their utility for early diagnosis and community risk stratification.
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Early Shenfu Injection in Sepsis: Impact on Hemodynamics, Mortality, and Microcirculation in a Multicenter RCT
Posted inCritical Care Infectious Diseases news

Early Shenfu Injection in Sepsis: Impact on Hemodynamics, Mortality, and Microcirculation in a Multicenter RCT

Posted by By MedXY 07/17/2026
Early administration of Shenfu injection in septic ICU patients did not reduce vasopressor use but was associated with lower mortality and improved microcirculation, warranting further validation.
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Wine Consumption, Mediterranean Diet, and Cardiovascular Risk in Two Spanish Cohorts
Posted inCardiology news Public Health

Wine Consumption, Mediterranean Diet, and Cardiovascular Risk in Two Spanish Cohorts

Posted by By MedXY 07/14/2026
This study from two Spanish cohorts explores how moderate wine consumption within a Mediterranean diet impacts cardiovascular disease and mortality, suggesting modest benefits but advising cautious interpretation.
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Impact of Modified Frailty Index on Liver Transplant Outcomes: Insights from a Multicenter Cohort Study
Posted inGastroenterology General Surgery news

Impact of Modified Frailty Index on Liver Transplant Outcomes: Insights from a Multicenter Cohort Study

Posted by By MedXY 07/08/2026
This study demonstrates that the 5-variable Modified Frailty Index effectively predicts short- and long-term morbidity and mortality after liver transplantation, supporting its use in pretransplant assessment and perioperative planning.
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Impact of Multidimensional Social Adversity on Mortality and Rehospitalization in People with HIV and Heart Failure
Posted inCardiology news

Impact of Multidimensional Social Adversity on Mortality and Rehospitalization in People with HIV and Heart Failure

Posted by By MedXY 07/02/2026
This study explores how various social adversity domains affect mortality and rehospitalization risks in HIV-positive patients with heart failure, underscoring the importance of holistic social assessments for improving outcomes.
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Postoperative Atrial Fibrillation After Cardiac Surgery: Common, Variably Treated, and Linked to Worse 1-Year Outcomes
Posted inCardiology news

Postoperative Atrial Fibrillation After Cardiac Surgery: Common, Variably Treated, and Linked to Worse 1-Year Outcomes

Posted by By MedXY 06/17/2026
The VISION Cardiac Surgery cohort found POAF in about one-third of patients, with wide variation in discharge treatment. POAF strongly predicted later atrial fibrillation and was associated with higher 1-year mortality.
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Exploring the Impact of Body Mass Index on Heart Failure Outcomes: Insights from Mendelian Randomization
Posted inCardiology news

Exploring the Impact of Body Mass Index on Heart Failure Outcomes: Insights from Mendelian Randomization

Posted by By MedXY 06/10/2026
This study leverages Mendelian randomization to demonstrate that genetically elevated BMI is associated with increased mortality and adverse cardiovascular outcomes in heart failure, irrespective of ejection fraction status, underscoring potential benefits of weight management.
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Body Mass Index, Clinical Outcomes, and Mortality in Heart Failure: A Mendelian Randomization Study
Posted inCardiology news

Body Mass Index, Clinical Outcomes, and Mortality in Heart Failure: A Mendelian Randomization Study

Posted by By MedXY 06/10/2026
This study uses Mendelian randomization to show that higher genetically predicted BMI is associated with increased all-cause mortality and cardiovascular events in heart failure patients, regardless of ejection fraction status.
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Higher Interleukin-6 Levels Predict Broad Cardiovascular Risk and Mortality Across Diverse Cohorts
Posted inCardiology Internal Medicine news

Higher Interleukin-6 Levels Predict Broad Cardiovascular Risk and Mortality Across Diverse Cohorts

Posted by By MedXY 05/31/2026
A pooled analysis of 59,396 participants found that higher serum IL-6 concentrations independently predicted nine cardiovascular and mortality outcomes, with consistent associations across key clinical subgroups.
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Health Plan Disenrollment and Mortality After Starting Medications for Opioid Use Disorder
Posted innews Psychiatry Public Health

Health Plan Disenrollment and Mortality After Starting Medications for Opioid Use Disorder

Posted by By MedXY 05/23/2026
A large cohort study found that health plan disenrollment after starting buprenorphine or naltrexone for opioid use disorder was linked to higher all-cause and overdose mortality, highlighting the importance of continuous coverage and treatment access.
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  • Hospital Variation in Early Tracheostomy and Life-Sustaining Treatment Withdrawal in Severe TBI: Insights from a Nationwide Study
  • Exploring ICU Staff Perspectives on Brain Death: Insights from a Swiss Multicenter Survey
  • International Validation of Sepsis Temperature-Trajectory Subphenotypes Reveals Immune and Coagulation Profiles with Implications for Immunoglobulin Therapy
  • Enhancing Hospital Discharge Prediction with Optimized Large Language Models: A Retrospective Cohort Study
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