Pediatrics – Page 7

Genetic Insights into Childhood Blood Pressure and Heart Rate: Implications for Adult Cardiometabolic Health

By MedXY 09/04/2026

Large-scale GWAS highlight novel genetic loci influencing childhood blood pressure and heart rate, with polygenic risk scores predicting adult cardiometabolic outcomes, underscoring the importance of early-life genetic determinants in cardiovascular risk stratification and prevention.

Cardiology news Pediatrics

VRONI Study: Advancing Pediatric Genetic Screening for Familial Hypercholesterolaemia to Improve Early Cardiovascular Health

By MedXY 09/04/2026

The VRONI study demonstrates the feasibility and effectiveness of combined biochemical and genetic screening for familial hypercholesterolaemia (FH) in children, revealing a higher FH prevalence than previously reported and supporting national pediatric screening initiatives.

Critical Care Infectious Diseases news Pediatrics

Optimizing Antibiotic Duration in Neonatal Early-Onset Sepsis: Evidence from the DURATION Trial

By MedXY 09/04/2026

A Danish multicentre trial demonstrates that individualized, clinically guided antibiotic treatment lasting around 3 days is as safe as the standard 5-7 days in late-preterm and term neonates with culture-negative early-onset sepsis, significantly reducing antibiotic exposure.

Clinical Updates news Pediatrics Public Health

Immunogenicity and Safety of Pentavalent Meningococcal MenABCWY Vaccine in Adolescents and Young Adults: Integrated Evidence from Late-Phase Clinical Trials

By MedXY 09/04/2026

This review synthesizes phase 2 and 3 trial data demonstrating that the pentavalent MenABCWY vaccine is immunologically non-inferior and well tolerated compared with MenB-fHbp and MenACWY-CRM vaccines, offering a simplified, effective vaccination strategy against invasive meningococcal disease in adolescents and young adults.

news Pediatrics Public Health

Screen Use and Children’s Language Development From Ages 5 to 7 Years

By MedXY 09/04/2026

This study examines the relationship between children's and parents' screen use and language development in children aged 5 to 7 years, finding parental smartphone use may slow vocabulary growth, while device ownership correlates with lower initial language skills.

Neurology news Pediatrics

Prenatal Organophosphate Exposure and Autism Traits: A Large-Scale Cohort Study Finds No Association

By MedXY 09/04/2026

This large prospective cohort study found no significant association between prenatal organophosphate pesticide exposure and autism-related traits in children, after comprehensive adjustments including maternal diet and sociodemographic factors.

Critical Care Infectious Diseases news Pediatrics

Evolving Trends in Late-Onset Sepsis Among Very Preterm Infants: Insights From a 14-Year Population-Based Study

By MedXY 09/04/2026

Late-onset sepsis (LOS) incidence among very preterm infants declined from 2010 to 2017 but has risen since, driven mainly by increasing infections from non-CoNS gram-positive bacteria and gram-negative pathogens, notably Staphylococcus aureus and Klebsiella species.

Clinical Updates Hematology-Oncology news Pediatrics

Reevaluating the Role of Direct Antiglobulin Testing in Low-Risk Neonates with ABO or RhD Incompatibility

By MedXY 09/04/2026

Routine DAT offers limited additional clinical value over transcutaneous bilirubin monitoring in low-risk ABO and RhD-incompatible neonates, supporting guideline shifts towards selective DAT use and emphasizing maternal antibody screening.

Hematology-Oncology news Pediatrics

Navigating Therapeutic Approaches in Pediatric Relapsed Acute Myeloid Leukemia: Current Trends and Comparative Outcomes

By MedXY 09/03/2026

This article reviews the variability and comparative effectiveness of re-induction treatments in pediatric relapsed AML, highlighting the role of gemtuzumab ozogamicin and chemotherapy backbones in improving remission rates but not overall survival.

General Surgery news Pediatrics

Redefining Functional Status Scale Thresholds to Improve Disability Detection in Pediatric Trauma Patients

By MedXY 09/02/2026

This study demonstrates that classifying a Functional Status Scale score of 7 as normal underestimates long-term disability in injured children, advocating for revised scoring cutoffs and routine follow-up assessments to enhance outcome detection.

Critical Care news Pediatrics

Evolving Trends in Pediatric Critical Care in the U.S. from 2001 to 2022: Implications for Healthcare Capacity and Regionalization

By MedXY 09/01/2026

Pediatric ICU admissions in the U.S. have increased significantly from 2001 to 2022, with rising complexity and costs, highlighting the need for expanded critical care resources and regionalized care.

Diabetes & Endocrinology news Pediatrics

Bone Health Index: A Novel Fracture Risk Assessment in Pediatric Osteogenesis Imperfecta

By MedXY 09/01/2026

The Bone Health Index (BHI), derived from metacarpal radiographs, predicts fracture risk more effectively than DXA in children with Osteogenesis Imperfecta, especially infants under five where DXA is limited.

news Otorhinolaryngology Pediatrics

Enhancing Early Detection of Neonatal Hearing Loss: A Machine Learning Risk Stratification Approach

By MedXY 08/31/2026

This article discusses a novel machine learning-based tool, especially XGBoost, to predict hearing loss risk in high-risk neonates using clinical factors for targeted early intervention.

news Ophthalmology Pediatrics

Evaluating HOTV Versus Tumbling E Vision Tests for Effective Pediatric Screening

By MedXY 08/31/2026

This study compares HOTV and tumbling E vision tests in children aged 3 to 15, demonstrating HOTV's superior accuracy and suitability for children under 8, potentially reducing unnecessary referrals in pediatric vision screening.

Cardiology news Pediatrics

Low Ventricular Chamber Stiffness as a Marker of High-Risk Eccentric Remodeling in Fontan Circulation: Insights from the FORCE Registry

By MedXY 08/30/2026

Lower ventricular chamber stiffness predicts adverse outcomes in Fontan patients, revealing a high-compliance, eccentric remodeling phenotype distinct from traditional stiffening hypotheses.

Diabetes & Endocrinology news Pediatrics

Navigating Ethical Challenges in Pediatric Endocrinology: Case-Based Approaches and Principles

By MedXY 08/28/2026

This article explores ethical dilemmas in pediatric endocrinology through case studies, applying the four-principle framework to guide clinicians in managing complex patient scenarios effectively and compassionately.

Neurology news Pediatrics

Expanding Horizons: Eligibility and Implications of Thrombolysis in Pediatric Acute Ischemic Stroke

By MedXY 08/28/2026

This study evaluates the eligibility of children with acute ischemic stroke (AIS) for thrombolysis with tPA, revealing only 19% potential eligibility under current guidelines, and highlights opportunities to reconsider treatment in small-vessel AIS.

news OB/GYN & Women’s Health Pediatrics

Impact of Gestational Age and Fetal Size on Neurodevelopment from Infancy through Adolescence

By MedXY 08/28/2026

This study reveals that among term births, fetal size at birth more strongly predicts long-term neurodevelopmental outcomes than gestational age, with small-for-gestational-age infants demonstrating persistent academic challenges into adolescence.

news Pediatrics Urology

Enhanced Recovery After Surgery (ERAS) Improves Outcomes in Pediatric Lower Urinary Tract Reconstruction

By MedXY 08/28/2026

The PURSUE multicenter study demonstrates that implementing Enhanced Recovery After Surgery protocols in pediatric patients undergoing complex lower urinary tract reconstruction significantly improves adherence to perioperative care standards, reduces length of hospital stay, lowers opioid use, and decreases complication rates without increasing readmissions or pain scores.

Hematology-Oncology news Pediatrics

Epstein-Barr Virus Reactivation and PTLD in Pediatric Haploidentical HSCT: Incidence, Risks, and Clinical Outcomes

By MedXY 08/28/2026

This study analyzes EBV infection and PTLD incidence in pediatric haploidentical HSCT, identifying prior CAR-T therapy, CMV viremia, and TBI conditioning as significant risk factors, with implications for enhanced monitoring and preemptive treatments.