Autoantibody Screening in Sibling-Dominant Pediatric Relatives of Type 1 Diabetes Patients: Prevalence, Determinants, and Psychological Impact

Autoantibody Screening in Sibling-Dominant Pediatric Relatives of Type 1 Diabetes Patients: Prevalence, Determinants, and Psychological Impact

This multicentre Turkish study identifies ZnT8 autoantibodies as predominant in young siblings at risk for type 1 diabetes and highlights gestational age as a protective factor, while revealing significant anxiety changes in children and parents post-screening, underscoring the need for integrated immunological and psychological care.
Evaluating Complication Rates in Post-Weight-Loss Body Contouring: Comparing Surgery, GLP-1 Pharmacotherapy, Combination, and Lifestyle Approaches

Evaluating Complication Rates in Post-Weight-Loss Body Contouring: Comparing Surgery, GLP-1 Pharmacotherapy, Combination, and Lifestyle Approaches

This study investigates postoperative complication rates following body-contouring surgery among patients with differing weight-loss methods, revealing that weight-loss modality does not affect complications, while BMI and diabetes at surgery are key predictors.
Glucagon-Like Peptide 1 Receptor Agonists, Mortality, and Cardiovascular Outcomes in Serious Mental Illness: A Comprehensive Review

Glucagon-Like Peptide 1 Receptor Agonists, Mortality, and Cardiovascular Outcomes in Serious Mental Illness: A Comprehensive Review

GLP-1 receptor agonists reduce mortality and cardiovascular events more effectively than SGLT2 inhibitors in serious mental illness (SMI), with early benefits and consistent effects across bipolar disorder, major depression, and schizophrenia. Semaglutide shows particular promise in improving cardiometabolic health.