Plasma Oxytocin as a Superior Preoperative Biomarker for Predicting Transient Postoperative Arginine Vasopressin Deficiency Following Transsphenoidal Pituitary Surgery

Plasma Oxytocin as a Superior Preoperative Biomarker for Predicting Transient Postoperative Arginine Vasopressin Deficiency Following Transsphenoidal Pituitary Surgery

This study identifies plasma oxytocin as a superior preoperative biomarker compared to copeptin for early prediction of transient arginine vasopressin deficiency after transsphenoidal pituitary surgery, aiding in risk stratification and postoperative management.
Longitudinal Changes in Cortisol Secretion and Cardiometabolic Outcomes in Benign Adrenal Incidentalomas: Insights from a Large Retrospective Cohort

Longitudinal Changes in Cortisol Secretion and Cardiometabolic Outcomes in Benign Adrenal Incidentalomas: Insights from a Large Retrospective Cohort

This study examines how temporal cortisol secretion changes in benign adrenal incidentalomas relate to long-term cardiometabolic outcomes and mortality, highlighting the significance of persistent mild autonomous cortisol secretion for hypertension management.
Human versus Analogue Insulin for Youth with Type 1 Diabetes in Low-Resource Settings: Insights from the HumAn-1 Trial and Complementary Evidence

Human versus Analogue Insulin for Youth with Type 1 Diabetes in Low-Resource Settings: Insights from the HumAn-1 Trial and Complementary Evidence

The HumAn-1 trial found no significant differences between insulin glargine and human isophane insulin in hypoglycemia risk or glucose control in young T1D patients in low-resource settings, underscoring accessibility over insulin type in these contexts.
Development and Validation of a Noninvasive Score for At-Risk Metabolic Dysfunction-Associated Steatohepatitis in Individuals with Obesity Undergoing Bariatric Surgery

Development and Validation of a Noninvasive Score for At-Risk Metabolic Dysfunction-Associated Steatohepatitis in Individuals with Obesity Undergoing Bariatric Surgery

Researchers developed and validated the FMO score, a noninvasive, cost-effective tool to identify at-risk metabolic dysfunction-associated steatohepatitis (MASH) in obese patients, showing strong predictive performance across multiple international cohorts.