MedXY – Page 16

Race-Neutral eGFR and Kidney Transplant Equity: Early Impacts on Black Patients at a Single Center

By MedXY 10/28/2026

A new OPTN policy removing race from eGFR calculations shows promise in increasing kidney transplantation access for Black patients by adding waiting time credits, while not disadvantaging others on the waitlist.

口服双重 JAK1/TYK2 抑制剂 QY201 在中重度特应性皮炎中疗效与安全性可期：2 期剂量探索试验结果

Allergy & Immunology Dermatology news

QY201, a Dual JAK1/TYK2 Inhibitor, Shows Promising Efficacy and Safety in Moderate-to-Severe Atopic Dermatitis: Phase 2 Dose-Finding Trial Results

By MedXY 10/28/2026

In a phase 2 trial, oral QY201 significantly improved skin outcomes in moderate-to-severe atopic dermatitis with favorable safety, supporting further phase 3 evaluation.

news Plastic Surgery

Revolutionizing Plastic Surgery: The Promise of Partial Cellular Reprogramming

By MedXY 10/28/2026

Partial cellular reprogramming harnesses Yamanaka factors to rejuvenate aging cells without losing identity, offering transformative potential in plastic surgery and regenerative medicine.

Internal Medicine news Public Health

Navigating the Balance: Fostering Humanistic Practice Amidst Healthcare System Pressures

By MedXY 10/27/2026

This qualitative study explores practicing physicians’ experiences with humanistic practice, revealing how relationships and resilience foster compassion despite systemic challenges like efficiency demands and standardized care models.

Hematology-Oncology news

Targeting IL-6 Receptor Signaling Enhances Cytolytic CD4+ T Cells and Improves Outcomes After Cellular Immunotherapy

By MedXY 10/27/2026

IL-6 receptor inhibition during hematopoietic stem cell transplantation fosters type I interferon responses and promotes expansion of cytolytic CD4+ T cells, including Eomes+ subsets, augmenting antitumor immunity while mitigating graft-versus-host disease.

Critical Care news Public Health

Global Disparities in Intensive Care Unit Resources and Organization: Insights from the ISOREA Survey

By MedXY 10/27/2026

The ISOREA survey highlights significant geo-economic disparities in ICU resources and organization worldwide, revealing critical gaps in critical care capabilities particularly in low-income settings, with implications for global health equity.

news Ophthalmology Superintelligence

Quantitative Vascular Severity Scoring Enhances Insights into Retinopathy of Prematurity Across Diverse Populations

By MedXY 10/27/2026

This study compares retinopathy of prematurity severity in US and Indian infants using an AI-derived vascular severity score, revealing epidemiological and pathophysiological differences that could impact diagnosis and management globally.

news Oncology Otorhinolaryngology

Swallowing Outcomes Following Early Treatment of Head and Neck Cancer-Related Lymphedema

By MedXY 10/27/2026

Early intervention for head and neck cancer-related lymphedema significantly improves swallowing function and patient-reported outcomes, supporting timely multidisciplinary care.

General Surgery news Oncology

Tailoring Prognostication in Pancreatic Ductal Adenocarcinoma: Impact of Neoadjuvant Therapy on Survival Predictors

By MedXY 10/27/2026

Neoadjuvant therapy alters key prognostic factors in resected pancreatic ductal adenocarcinoma, enabling personalized survival prediction models distinct from chemo-naïve patients.

HPV 疫苗接种年轻女性的细胞学与高危型 HPV 检测评估：来自苏格兰前瞻性研究的启示

Infectious Diseases news OB/GYN & Women's Health

Evaluating Cytology and High-Risk HPV Testing in HPV-Vaccinated Young Women: Insights from a Scottish Prospective Study

By MedXY 10/27/2026

This prospective Scottish study compares cytology and high-risk HPV testing performance in young HPV-vaccinated women, revealing high negative predictive value but lower positive predictive value of hrHPV testing, emphasizing the role of cytology triage in cervical screening.

Clinical Updates Neurology news

Systemic Fluoroquinolones and Peripheral Neuropathy Risk: Comprehensive Evidence Review and Clinical Implications

By MedXY 10/27/2026

A thorough review of systemic fluoroquinolone use reveals minimal association with peripheral neuropathy risk compared to cephalosporins, supported by large cohort studies and pharmacovigilance data, guiding safer antibiotic prescribing.

Cardiology Diabetes & Endocrinology news

A Recipe for Better Diabetes Management: Embracing the DASH4D Dietary Pattern

By MedXY 10/27/2026

The DASH4D diet, a diabetes-adapted version of the DASH eating plan, significantly improves blood pressure and blood sugar control in type 2 diabetes with hypertension, offering a strong evidence-based dietary recommendation for personalized nutrition therapy.

Allergy & Immunology Cardiology news

Impact of Familial Hypercholesterolaemia on Thymic Ageing: Insights from a Large Chinese Cohort

By MedXY 10/27/2026

This study reveals that familial hypercholesterolaemia accelerates thymic ageing, reducing thymic output and altering T-cell diversity; statin therapy partially preserves thymic function, suggesting integrated metabolic-immunologic management in FH.

news Orthopedics

Enhanced Healing and Zone-Specific Cartilage Protection With Concomitant Meniscal Centralization in Medial Meniscus Posterior Root Repair: Insights From a Rabbit Model

By MedXY 10/27/2026

This study demonstrates that combining meniscal centralization with medial meniscus posterior root repair reduces cartilage degeneration and improves healing compared with isolated root repair, revealing zone-specific cartilage preservation in the medial femoral condyle.

Neurology news Psychiatry

Understanding Loneliness in Traumatic Spinal Cord Injury: Psychosocial Correlates and Clinical Implications

By MedXY 10/27/2026

Loneliness in individuals with traumatic spinal cord injury correlates strongly with environmental barriers and depressive symptoms, highlighting the interplay of internal and external factors in mental health outcomes.

Dentistry General Surgery news

Ten-Year Outcomes of Surgical Intervention for Peri-Implantitis Using Bovine Bone Collagen Matrix, Enamel Matrix Derivative, and Doxycycline

By MedXY 10/27/2026

A 10-year prospective cohort study demonstrates high implant survival and clinical stability following surgical peri-implantitis treatment combining DBBMC, enamel matrix derivative, doxycycline, and tailored supportive therapy.

news Oncology

Advancing Treatment in ER-Positive, HER2-Negative Advanced Breast Cancer: Efficacy of Giredestrant Plus Everolimus

By MedXY 10/27/2026

A phase 3 trial demonstrates that the oral combination of giredestrant and everolimus significantly improves progression-free survival in patients with ER-positive, HER2-negative advanced breast cancer post-CDK4/6 inhibitor therapy, especially in ESR1-mutated tumors, with a manageable safety profile.

Dermatology news Superintelligence

Enhancing Lentigo Maligna Detection with AI-Assisted Dermoscopy: A Clinical Reader Study on Facial Pigmented Lesions

By MedXY 10/27/2026

A deep learning model significantly improves lentigo maligna detection and dermatology resident diagnostic accuracy when applied to dermoscopic images of facial pigmented lesions, underscoring AI's adjunctive role in clinical dermatology and training.

Clinical Updates news OB/GYN & Women's Health Plastic Surgery

Impact of Substantial Preoperative Weight Loss on Postoperative Outcomes and Healthcare Utilization Following Reduction Mammoplasty in Obese Patients

By MedXY 10/27/2026

Recent substantial preoperative weight loss (>10%) in obese patients undergoing reduction mammoplasty is associated with increased surgical site infections and hospital readmissions compared to weight-stable obese patients, highlighting complexities beyond BMI in surgical risk assessment.

Critical Care news Psychiatry

Persistent Mental Health Challenges Among Caregivers of ICU Sepsis Survivors: Links to Patient Post-Intensive Care Syndrome

By MedXY 10/27/2026

A prospective study reveals that caregivers of ICU sepsis survivors frequently suffer long-lasting mental health issues strongly linked to patients' mental impairments, underscoring the need for targeted mental health support.