survival outcomes

$Maximizing Outcomes in Locally Advanced Pancreatic Cancer with Hypofractionated Ablative Radiation Therapy$

Maximizing Outcomes in Locally Advanced Pancreatic Cancer with Hypofractionated Ablative Radiation Therapy

By MedXY 08/02/2026

Hypofractionated ablative radiation therapy after induction chemotherapy shows promise in patients with locally advanced pancreatic cancer, improving resectability and 2-year survival while maintaining acceptable safety profiles.

news OB/GYN & Women’s Health Oncology

MLH1 Promoter Hypermethylation Does Not Impact Survival Outcomes in dMMR Endometrial Cancer Treated with Immune Checkpoint Inhibitors

By MedXY 08/01/2026

This study analyzes real-world data showing that MLH1 promoter hypermethylation and Lynch syndrome-associated genetic mutations confer similar response rates and survival outcomes in mismatch repair deficient endometrial cancer treated with immune checkpoint inhibitors.

Gastroenterology news Oncology

Comparing FLOT and CROSS Protocols: Survival and Recurrence in Esophageal Adenocarcinoma with Pathological Complete Response

By MedXY 07/24/2026

This cohort study compares long-term survival and recurrence in esophageal adenocarcinoma patients achieving pathological complete response (pCR) after neoadjuvant FLOT chemotherapy versus CROSS chemoradiotherapy, highlighting better outcomes with FLOT.

Dermatology news Oncology

Exploring Institutional and Insurance-Linked Disparities in Melanoma Outcomes: Insights from a VA and Tertiary Care Cohort Study

By MedXY 07/14/2026

This cohort study reveals differential melanoma survival outcomes linked to institutional settings and insurance types, highlighting the need for standardized care in advanced melanoma stages.

Cardiology Critical Care news

Evaluating the Impact of the Resuscitation Quality Improvement Program on In-Hospital Cardiac Arrest Outcomes

By MedXY 07/12/2026

A national cohort study found that adoption of the Resuscitation Quality Improvement (RQI) program for CPR training did not improve survival to discharge or return of spontaneous circulation in patients experiencing in-hospital cardiac arrest, highlighting the need for more comprehensive strategies.

news OB/GYN & Women’s Health Oncology

Estrogen Therapy Linked to Improved Survival in Certain Ovarian Cancer Patients Under 60

By MedXY 05/11/2026

Study shows post-diagnosis estrogen therapy improves survival in high-grade serous and clear cell ovarian cancers but may worsen outcomes in endometrioid subtypes, offering guidance for managing menopausal symptoms in younger survivors.

news Oncology Otorhinolaryngology

Impact of Immunocompromise on Survival in HPV-Positive Throat Cancer Patients

By MedXY 05/08/2026

This study examines how pre-existing immunocompromise affects survival and outcomes in patients with HPV-positive oropharyngeal cancer treated surgically. Immunocompromised patients showed significantly worse overall survival compared to non-immunocompromised peers, underscoring the need for personalized care strategies.

Infectious Diseases Neurology news

Combination Antiviral Therapy Improves Survival in HHV-6B Encephalitis Post-Cord Blood Transplant

By MedXY 04/24/2026

A real-world study reveals FCN/GCV combination therapy enhances 1-year survival in HHV-6B encephalitis post-CBT, particularly after neutrophil engraftment, compared to monotherapy. Findings underscore the need for tailored antiviral strategies based on hematologic recovery.

Hematology-Oncology Internal Medicine news

Blast-Phase MPNs: One-Third Achieve Long-Term Survival with Allogeneic Transplantation

By MedXY 04/21/2026

Allogeneic hematopoietic stem cell transplantation offers a potential cure for blast-phase myeloproliferative neoplasms, with one-third of patients achieving long-term survival. Key factors influencing outcomes include TP53 mutations and peripheral blast burden.

Clinical Updates Gastroenterology news Oncology

Proton Pump Inhibitor Use and Survival Outcomes in Newly Diagnosed Glioblastoma: An Evidence-Based Review

By MedXY 12/14/2025

Proton pump inhibitor use, particularly potent ALDH1A1-activating PPIs, is associated with worse survival in newly diagnosed glioblastoma, highlighting the need for cautious use and further mechanistic research.

news Oncology Urology

Evolving Treatment Patterns and Survival Outcomes in Veterans With De Novo Metastatic Hormone-Sensitive Prostate Cancer

By MedXY 10/30/2025

A retrospective study in US veterans reveals increased use of combination therapies for metastatic hormone-sensitive prostate cancer (mHSPC), showing improved survival over ADT alone. ARPIs and docetaxel demonstrate comparable overall survival, with ARPIs providing longer progression-free survival.

news OB/GYN & Women's Health Oncology Radiology Specialties

Impact of Immediate Past Mammography Participation on Outcomes of Screen-Detected Breast Cancer

By MedXY 10/04/2025

This cohort study reveals that women with screen-detected breast cancer who missed the immediate prior mammography screening have larger tumors, more advanced disease, and worse breast cancer-specific survival, suggesting delayed detection and poorer prognosis.

news OB/GYN & Women's Health Oncology Specialties

Impact of Treatment Recommendation and Receipt on Survival in Older Women with Early-Stage Cervical Cancer

By MedXY 09/24/2025

This study reveals that among women aged 65 and older with early-stage cervical cancer, those who receive recommended treatment—surgery and/or radiotherapy—exhibit significantly higher survival rates, emphasizing the need to overcome treatment barriers in this population.

Clinical Updates Hematology-Oncology Specialties

Unraveling the Prognostic Impact of Co-Occurring High-Risk Cytogenetic Abnormalities in Multiple Myeloma

By MedXY 09/09/2025

A meta-analysis of 24 trials involving 13,926 patients establishes that concurrent high-risk cytogenetic abnormalities markedly worsen progression-free and overall survival in both newly diagnosed and relapsed multiple myeloma, underscoring the need for targeted therapeutic strategies.

news Oncology Specialties

Local Recurrence and Survival Outcomes in Non-Lentigo Maligna and Non-Acral Lentiginous Melanoma In Situ: Evidence from a 30-Year Cohort Study

By MedXY 09/03/2025

This retrospective cohort study evaluates local recurrence and survival in non-LM/non-ALM melanoma in situ, revealing minimal recurrence rates when diagnostic excisional biopsies have clear margins, questioning the necessity of routine wide excisions.

news OB/GYN & Women's Health Oncology Specialties

Age-Dependent Survival Outcomes in Early-Stage Endometrial Cancer: Fertility-Preserving Hormonal Therapy Versus Hysterectomy

By MedXY 08/31/2025

Fertility-preserving hormonal therapy for early-stage endometrial cancer shows comparable 5-year survival to hysterectomy in women under 40, but a significantly higher mortality risk in those aged 40-49 years, highlighting age as a critical factor in treatment decisions.

Oncology Radiology Specialties

Adjuvant Chemoradiotherapy in Oral Cavity SCC: Distinguishing Benefits Between Minor and Major Extranodal Extension

By MedXY 08/23/2025

This multicenter study clarifies that adjuvant chemotherapy improves survival outcomes in oral cavity squamous cell carcinoma with major extranodal extension but offers no clear benefit in cases with minor extranodal extension.

Family Medicine & Nutrition news Oncology Specialties

Structured Exercise after Adjuvant Chemotherapy for Colon Cancer: Impact on Survival Outcomes

By MedXY 08/19/2025

A 3-year structured exercise program post-adjuvant chemotherapy significantly improves disease-free and overall survival in colon cancer patients, based on the CHALLENGE phase 3 RCT involving 889 patients.