Comparing CHOP and CHOEP/EPOCH Regimens in Aggressive Adult T-Cell Leukemia/Lymphoma: Insights from an International Cohort Study

Highlight

  • CHOEP/EPOCH regimens show improved 3-year overall survival compared to CHOP in lymphomatous adult T-cell leukemia/lymphoma (ATL).
  • No significant survival benefit of CHOEP/EPOCH over CHOP was observed in acute ATL.
  • Overall response rates between regimens were not statistically different across ATL subtypes.
  • The study underscores the need for subtype-specific prospective clinical trials in aggressive ATL management.

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