可穿戴技术与医院衰弱风险评分的融合：破解偏倚，推动衰弱评估公平化
Posted inClinical Updates Internal Medicine Superintelligence

Integrating Wearable Technology with Hospital Frailty Risk Score: Addressing Bias and Promoting Equity in Frailty Assessment

Wearable devices offer continuous, real-world data to enhance frailty assessments beyond conventional episodic clinical measures. Combining this data with the Hospital Frailty Risk Score (HFRS) facilitates earlier detection and intervention, yet necessitates measures against biases and inequities to ensure equitable care.
英国高龄肾衰竭及衰弱患者的响应式管理与肾透析的比较有效性：“肾脏护理准备”（Prepare for Kidney Care）试验
Posted inClinical Updates Nephrology

Comparative Effectiveness of Responsive Management Versus Renal Dialysis in Elderly UK Patients with Kidney Failure and Frailty: Insights from the Prepare for Kidney Care Trial and Related Advances

This review synthesizes evidence from the Prepare for Kidney Care trial and complementary studies, highlighting that in older frail or multimorbid kidney failure patients, responsive management offers similar quality-adjusted life expectancy as dialysis, with fewer access complications, informing patient-centered decision-making.
Intensive Blood Pressure Control to <120 mmHg: Holistic Benefits Across Frailty, Quality of Life, and Microvascular Health in the ESPRIT Trial
Posted inCardiology Internal Medicine news

Intensive Blood Pressure Control to <120 mmHg: Holistic Benefits Across Frailty, Quality of Life, and Microvascular Health in the ESPRIT Trial

The ESPRIT trial reveals that targeting systolic blood pressure below 120 mmHg significantly reduces cardiovascular events across diverse populations, including frail patients and those with diabetes, while uniquely improving retinal microvascular health and maintaining patient quality of life.
Frailty Amplifies Mortality Risk Across the PaO2/FiO2 Spectrum: Insights from a 497,185‑Patient ANZICS Cohort
Posted inCritical Care news Respiratory

Frailty Amplifies Mortality Risk Across the PaO2/FiO2 Spectrum: Insights from a 497,185‑Patient ANZICS Cohort

In a 497,185‑patient registry study, frailty (CFS ≥5) was common and associated with substantially higher in‑hospital mortality across all severities of acute hypoxemic respiratory failure (AHRF). The relationship between PaO2/FiO2 and death was nonlinear and distinctly separated by frailty category.
Home-Based Prehabilitation Did Not Reduce Disability or Complications in Older Adults with Frailty: Results of a Pragmatic Multicenter RCT
Posted inAnesthesiology General Surgery news Rehabilitation Medicine

Home-Based Prehabilitation Did Not Reduce Disability or Complications in Older Adults with Frailty: Results of a Pragmatic Multicenter RCT

A pragmatic multicenter randomized trial found that coach-supported, home-based multimodal prehabilitation before elective noncardiac surgery did not reduce 30-day postoperative disability or in-hospital complications in older adults with frailty; higher adherence signaled possible benefit for disability outcomes.