Specialties – Page 23

Adrenalectomy for Mild Autonomous Cortisol Secretion Was Linked to Lower Mortality, but the Survival Signal Requires Cautious Interpretation

By MedXY 05/11/2026

In a multi-institutional retrospective cohort, adrenalectomy for mild autonomous cortisol secretion was associated with lower mortality and less new-onset diabetes than nonoperative care, although sensitivity analysis weakened the survival finding.

Diabetes & Endocrinology General Surgery news

Biliopancreatic Diversion for Severe Obesity: Landmark 50-Year Study Reveals Lifelong Benefits and Risks

By MedXY 05/11/2026

A 50-year follow-up of biliopancreatic diversion shows sustained weight loss and diabetes remission, but alarmingly high nutritional complications decades after surgery.

news OB/GYN & Women’s Health Oncology

Estrogen Therapy Linked to Improved Survival in Certain Ovarian Cancer Patients Under 60

By MedXY 05/11/2026

Study shows post-diagnosis estrogen therapy improves survival in high-grade serous and clear cell ovarian cancers but may worsen outcomes in endometrioid subtypes, offering guidance for managing menopausal symptoms in younger survivors.

news OB/GYN & Women’s Health Public Health

Low-Dose Aspirin’s Pregnancy Benefit Appears Unchanged by Start Time or Adherence in a Large Multicentre Post Hoc Trial Analysis

By MedXY 05/11/2026

In this post hoc analysis of a large randomized pregnancy trial, aspirin’s effects on preterm birth and perinatal mortality were not meaningfully modified by gestational age at initiation or measured adherence.

Infectious Diseases news OB/GYN & Women’s Health

First-Trimester Maternal CMV Infection Concentrates the Risk of Fetal Brain Injury, Hearing Loss, and Autism Spectrum Disorder

By MedXY 05/11/2026

A large prospective cohort suggests that long-term sequelae of congenital CMV after primary maternal infection are confined to first-trimester exposure, with autism spectrum disorder linked to temporal lobe white matter abnormalities.

Gastroenterology news Oncology

A Body Surface Area–Adjusted Bevacizumab Target Was Linked to Better Survival in Atezolizumab-Treated Unresectable Hepatocellular Carcinoma

By MedXY 05/10/2026

A nationwide Japanese real-world study suggests that a defined body surface area–adjusted bevacizumab exposure range may improve progression-free and overall survival in unresectable HCC treated with atezolizumab plus bevacizumab, without increasing toxicity.

Gastroenterology news Oncology

A Stromal CTHRC1 Biomarker Framework May Identify Colorectal Cancers With Poor Prognosis and Limited Immunotherapy Benefit

By MedXY 05/10/2026

A large multiomic colorectal cancer study identifies CTHRC1-positive fibroblasts as a stromal biomarker linked to TGF-beta activity, adverse outcomes, and reduced checkpoint inhibitor benefit across both MSI and MSS disease.

Neurology news Public Health

Weak Grip, Slow Walking Pace, and Sarcopenia Signal Higher Risk of Incident Stroke and Worse Poststroke Survival in UK Biobank

By MedXY 05/10/2026

In nearly 483,000 UK Biobank participants, sarcopenia, low grip strength, and slow walking pace were associated with higher risks of incident stroke and poorer survival after stroke.

Neurology news

Multiple Sclerosis End-of-Life Care Remains Hospital-Centered Despite Comparable Palliative Care Use

By MedXY 05/10/2026

A large Ontario population study found that people with multiple sclerosis received palliative care at rates similar to other decedents, yet rural inequities and frequent hospital death persisted, highlighting the need for earlier neuropalliative integration.

Emergency Medicine Neurology news

Adjunct Intra-arterial Alteplase After Successful Basilar Thrombectomy Was Safe but Did Not Improve 90-Day Outcomes in IAT-TOP

By MedXY 05/10/2026

In the IAT-TOP randomized trial, intra-arterial alteplase after successful EVT for acute basilar artery occlusion did not improve 90-day functional independence, while symptomatic intracranial hemorrhage and mortality were similar between groups.

Cardiology Diabetes & Endocrinology news

Subclinical Hyperthyroidism Carries Measurable Risks of Atrial Fibrillation, Heart Failure, and Death in Primary Care

By MedXY 05/10/2026

A large Dutch primary care cohort links subclinical hyperthyroidism to higher risks of atrial fibrillation, heart failure, and all-cause mortality, with particularly notable relative risks in younger adults and in patients with more strongly suppressed TSH.

Diabetes & Endocrinology news Radiology

Advanced Liver Imaging Reveals Impaired Postprandial Hepatic Glucose Handling and Hidden Metabolic Subtypes in Type 1 Diabetes

By MedXY 05/10/2026

A 7 T imaging and tracer study found that adults with type 1 diabetes have abnormal postprandial hepatic glucose uptake, blunted glycogen storage, reduced suppression of endogenous glucose production, and marked metabolic heterogeneity despite similar systemic insulin exposure.

Diabetes & Endocrinology news Pediatrics

Glucocorticoid Reduction After Starting Crinecerfont in Pediatric Patients With Classic CAH: Practical Perspectives

By MedXY 05/10/2026

New expert recommendations guide glucocorticoid dose reduction in pediatric classic CAH patients using crinecerfont, prioritizing normal growth while minimizing long-term steroid complications.

Diabetes & Endocrinology news Pediatrics

Pediatric Type 1 Diabetes Care Still Misses LDL Targets Despite Clear Indications for Lipid-Lowering Therapy

By MedXY 05/10/2026

Registry data from 55,028 youths with type 1 diabetes show common LDL hypercholesterolemia, infrequent lipid-lowering therapy, and poor attainment of recommended LDL targets.

Diabetes & Endocrinology news Public Health

Multi-ancestry Polygenic Risk Scores Substantially Improve Type 2 Diabetes Risk Prediction Across Diverse Populations

By MedXY 05/10/2026

A large multi-ancestry study shows that publicly available polygenic risk scores improve prediction of type 2 diabetes onset and selected microvascular complications across major global ancestry groups.

Cardiology news

Rationale and Design of CARDIO-TTRansform: A Phase 3 Trial of Eplontersen for Transthyretin Amyloid Cardiomyopathy

By MedXY 05/10/2026

CARDIO-TTRansform is a global Phase 3 trial evaluating eplontersen's efficacy and safety in reducing cardiovascular events in transthyretin amyloid cardiomyopathy patients receiving standard care, including TTR stabilizers. With 1,432 participants, it aims to establish a new treatment paradigm.

Cardiology news

Sex-Based Patterns and Trends in Transcatheter Aortic Valve Implantation

By MedXY 05/10/2026

A 10-year Medicare study reveals women face higher immediate risks during TAVI procedures but demonstrate better long-term survival than men, despite declining representation in treatment.

Cardiology Clinical Updates news

Optimizing Antiplatelet Strategies in Complex PCI: Insights from the TAILORED-CHIP Trial and Evolving Evidence for Temporal Modulation

By MedXY 05/09/2026

This review synthesizes the TAILORED-CHIP trial results with recent evidence on antiplatelet modulation, highlighting the challenges of balancing ischemic and bleeding risks in high-risk PCI populations.

Cardiology Emergency Medicine news

A New hs-cTnT Generation 6 Assay Matches Generation 5 for Myocardial Infarction Diagnosis While Labeling Fewer Patients as Myocardially Injured

By MedXY 05/09/2026

In suspected myocardial infarction, hs-cTnT-gen6 showed diagnostic accuracy comparable to gen5, produced fewer myocardial injury classifications, and supported highly sensitive ESC 0/1-hour and 0/2-hour rule-out and rule-in pathways using assay-specific cutoffs.

Cardiology news

Determining the Physiological Threshold for Angina (ORBITA-FIRE): A Double-Blind, Randomized, Placebo-Controlled Study

By MedXY 05/09/2026

ORBITA-FIRE study reveals personalized physiological thresholds for angina that are lower than current diagnostic standards. These thresholds vary during exercise and predict PCI treatment success, challenging universal ischemia-based guidelines.