Identification of two distinct peripheral retinal vascular phenotypes in retinitis pigmentosa (RP) via ultra-widefield OCT angiography (UWF-OCTA): Terminal Remodeling and Simple Atrophy.
Validation of the chorioretinal neovascular zone (CNZ) area as a robust quantitative biomarker correlating strongly with multiple visual function measures.
Development and validation of a clinically applicable four-stage severity grading system based on CNZ area reliably stratifying RP disease progression.
Potential for the grading system to enhance disease monitoring and patient stratification in future interventional trials.