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Internal Medicine

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  • Page 4
Effectiveness of Automatically-Adjusted vs Manually-Adjusted Noninvasive Ventilation in Obesity Hypoventilation Syndrome: A Randomized Clinical Trial
Posted inInternal Medicine news Respiratory

Effectiveness of Automatically-Adjusted vs Manually-Adjusted Noninvasive Ventilation in Obesity Hypoventilation Syndrome: A Randomized Clinical Trial

Posted by MedXY By MedXY 05/21/2026
In ambulatory patients with obesity hypoventilation syndrome, automatically-adjusted noninvasive ventilation was as effective as manually adjusted NIV over 12 months and more cost-effective, offering a simpler path to treatment.
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Fatigue After Thyroidectomy: What Patients Actually Experience
Posted inGeneral Surgery Internal Medicine news Otorhinolaryngology

Fatigue After Thyroidectomy: What Patients Actually Experience

Posted by MedXY By MedXY 05/20/2026
A qualitative study found that fatigue after thyroidectomy is common, disruptive, and often unexpected. Patients described major impacts on work and daily life, and many wanted surgeons to warn them about it before surgery.
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Telemedicine After the Pandemic: Who Benefits, What Changed, and What Comes Next
Posted inInternal Medicine news Public Health

Telemedicine After the Pandemic: Who Benefits, What Changed, and What Comes Next

Posted by MedXY By MedXY 05/18/2026
Telemedicine is no longer an emergency workaround. New policy guidance shows how virtual care can improve access, but only if payment, safety, equity, and prescribing rules evolve carefully.
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Cardiomyopathy Gene Therapy Reaches an Inflection Point: From AAV Delivery to Precision Genome Editing
Posted inCardiology Internal Medicine news

Cardiomyopathy Gene Therapy Reaches an Inflection Point: From AAV Delivery to Precision Genome Editing

Posted by MedXY By MedXY 05/12/2026
Gene therapy for cardiomyopathy is moving from concept to clinic, but durable benefit will depend on solving delivery, immunogenicity, cargo, and safety barriers in the failing human heart.
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Sacubitril/Valsartan Improved Exercise Pulmonary Hemodynamics and Dynamic Atrial Functional Mitral Regurgitation in HFpEF: Interpreting the PRAISE-MR Randomized Trial
Posted inCardiology Internal Medicine news

Sacubitril/Valsartan Improved Exercise Pulmonary Hemodynamics and Dynamic Atrial Functional Mitral Regurgitation in HFpEF: Interpreting the PRAISE-MR Randomized Trial

Posted by MedXY By MedXY 05/12/2026
In symptomatic HFpEF with atrial functional mitral regurgitation, sacubitril/valsartan improved exercise hemodynamics, peak VO2, symptoms, biomarkers, and stress-induced MR burden over 6 months versus standard care.
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Initiation of Medications for Alcohol Use Disorder Among Hospitalized Veterans : A Retrospective Cohort Study
Posted inInternal Medicine news Psychiatry

Initiation of Medications for Alcohol Use Disorder Among Hospitalized Veterans : A Retrospective Cohort Study

Posted by MedXY By MedXY 05/11/2026
VHA study reveals only 30% of veterans hospitalized for AUD receive evidence-based medications during or shortly after hospitalization, with significant variation across hospitals and demographic factors influencing prescription rates.
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低剂量聚乙二醇用于住院患者肠道准备的有效性：一项多中心随机试验
Posted inGastroenterology Internal Medicine news

低剂量聚乙二醇用于住院患者肠道准备的有效性：一项多中心随机试验

Posted by MedXY By MedXY 05/09/2026
意大利多中心研究发现，1升聚乙二醇抗坏血酸方案在住院患者结肠镜检查前肠道准备中，高质量清洁率显著优于2升和4升方案，且患者耐受性更好。
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甲状腺功能随年龄变化的自然历程：一项涵盖31项前瞻性队列研究的13.7万参与者个体数据分析
Posted inDiabetes & Endocrinology Internal Medicine news

甲状腺功能随年龄变化的自然历程：一项涵盖31项前瞻性队列研究的13.7万参与者个体数据分析

Posted by MedXY By MedXY 05/06/2026
大规模国际研究发现甲状腺功能随年龄变化存在性别和碘状态差异。虽然多数人甲状腺功能稳定且TSH轻微升高，但任何变化模式均与全因死亡风险增加1.8-2.5倍相关，这对老年甲状腺健康管理具有重要临床意义。
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Targeting Skeletal Muscle Myosin ATPase May Reduce Resting Energy Waste in Heart Failure With Reduced Ejection Fraction
Posted inCardiology Internal Medicine news

Targeting Skeletal Muscle Myosin ATPase May Reduce Resting Energy Waste in Heart Failure With Reduced Ejection Fraction

Posted by MedXY By MedXY 05/06/2026
An ex vivo human skeletal muscle study suggests that myosin ATPase inhibition with mavacamten normalizes excessive resting ATP consumption in HFrEF myofibres, identifying a mechanistically novel strategy to address peripheral metabolic inefficiency and exercise intolerance.
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Long-Term SAFE-PAD Data Reassure on Mortality After Paclitaxel-Coated Femoropopliteal Interventions
Posted inCardiology Internal Medicine news

Long-Term SAFE-PAD Data Reassure on Mortality After Paclitaxel-Coated Femoropopliteal Interventions

Posted by MedXY By MedXY 05/06/2026
In Medicare patients undergoing femoropopliteal revascularization, drug-coated devices were not associated with higher long-term mortality, supporting the safety of paclitaxel-coated technology after years of regulatory concern.
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PCSK9 Inhibition Lowers LDL Cholesterol in Heterozygous Familial Hypercholesterolemia Regardless of LDL Receptor Variant Function
Posted inCardiology Internal Medicine news

PCSK9 Inhibition Lowers LDL Cholesterol in Heterozygous Familial Hypercholesterolemia Regardless of LDL Receptor Variant Function

Posted by MedXY By MedXY 05/03/2026
In a pooled nonrandomized phase 3 analysis, monthly lerodalcibep reduced LDL-C by about 50% in heterozygous familial hypercholesterolemia, with similar efficacy across LDLR functional variant categories and broad attainment of guideline-based LDL-C goals.
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HSP72-PRDX6 Control of PINK1 Ubiquitination Emerges as a New Mitophagy Axis in MASLD
Posted inGastroenterology Internal Medicine news

HSP72-PRDX6 Control of PINK1 Ubiquitination Emerges as a New Mitophagy Axis in MASLD

Posted by MedXY By MedXY 05/01/2026
A new Hepatology study identifies an HSP72–PRDX6 pathway that restores PINK1/Parkin mitophagy, reduces hepatic steatosis, and worsens MASLD when disrupted in mice and hepatocytes.
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Posted inInternal Medicine news

Fontan Outcomes Network Enrolls 1,121 Patients and Reveals a High Burden of Arrhythmia, Thrombosis, and Mental Health Needs

Posted by Zhang Paul By Zhang Paul 04/30/2026
Background Fontan palliation has transformed the prognosis of children born with single-ventricle heart disease, allowing…
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Midlife Cardiorespiratory Fitness Linked to Extended Healthspan and Reduced Multimorbidity in Aging
Posted inCardiology Internal Medicine news

Midlife Cardiorespiratory Fitness Linked to Extended Healthspan and Reduced Multimorbidity in Aging

Posted by MedXY By MedXY 04/29/2026
Higher midlife cardiorespiratory fitness is associated with longer healthspan, fewer chronic diseases, and extended lifespan in men and women, based on a large observational cohort study linking clinical data to Medicare claims.
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Chronic Low Back Pain: Physical Therapy Outperforms CBT as First-Line Treatment
Posted inInternal Medicine news Orthopedics

Chronic Low Back Pain: Physical Therapy Outperforms CBT as First-Line Treatment

Posted by MedXY By MedXY 04/27/2026
A recent randomized trial found PT modestly improved function over CBT in cLBP, but no second-stage treatment differences emerged for nonresponders. The study informs adaptive treatment strategies.
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Mild and Single Moderate COPD Exacerbations Predict Future Risks: Insights from a Community-Based Cohort Study
Posted inInternal Medicine news Respiratory

Mild and Single Moderate COPD Exacerbations Predict Future Risks: Insights from a Community-Based Cohort Study

Posted by MedXY By MedXY 04/27/2026
Community-based COPD patients with mild or single moderate exacerbations show higher future exacerbation risks and lung structural abnormalities, despite stable lung function decline rates.
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Video Declarations: Bridging the Gap in Advanced Cancer Care Conversations
Posted inInternal Medicine news Oncology

Video Declarations: Bridging the Gap in Advanced Cancer Care Conversations

Posted by MedXY By MedXY 04/24/2026
A study explores how video declarations from advanced cancer patients can enhance goals of care discussions by focusing on decision-making factors rather than specific medical interventions, offering a patient-centered tool for advance care planning.
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Revolutionizing iTTP Treatment: Reverse CAR T Cells Target Autoreactive B Cells with Precision
Posted inHematology-Oncology Internal Medicine news

Revolutionizing iTTP Treatment: Reverse CAR T Cells Target Autoreactive B Cells with Precision

Posted by MedXY By MedXY 04/24/2026
A groundbreaking study introduces reverse CAR T cells to selectively deplete anti-ADAMTS13 autoreactive B cells in immune-mediated thrombotic thrombocytopenic purpura (iTTP), offering a novel, precise, and potentially safer therapeutic approach.
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Reevaluating TSH-FT4 Dynamics: New Evidence Challenges Traditional Reference Intervals
Posted inDiabetes & Endocrinology Internal Medicine news

Reevaluating TSH-FT4 Dynamics: New Evidence Challenges Traditional Reference Intervals

Posted by MedXY By MedXY 04/22/2026
A retrospective study reveals that the TSH-FT4 relationship is segmented, not log-linear, with implications for refining thyroid function test interpretation and reference intervals.
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Hospital Delays in Glucose Checks and Insulin Dosing: Do They Impact Patient Care?
Posted inDiabetes & Endocrinology Internal Medicine news

Hospital Delays in Glucose Checks and Insulin Dosing: Do They Impact Patient Care?

Posted by MedXY By MedXY 04/22/2026
Study reveals significant time gaps between fingerstick glucose tests and insulin administration in hospitals, with nearly 30% of cases potentially receiving incorrect insulin doses due to changing glucose levels during delays.
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  • Secondary Autoimmune and Inflammatory Diseases Post-Allogeneic Hematopoietic Stem Cell Transplantation: Incidence, Risk Factors, and Clinical Outcomes from the EBMT Registry
  • Cytogenetic Insights into Multiple Myeloma Outcomes Despite MRD Negativity Post-Autologous Stem Cell Transplant
  • CD19 CAR T-cell Therapy Without Lymphodepletion Shows Promise in Pemphigus Vulgaris: Insights from the RESET-PV Trial
  • Prognostic Impact of Single Moderate Exacerbation in COPD Patients: Insights from 12-Year Mortality and Future Exacerbation Risk Analysis
  • Acute Exacerbation in Fibrotic Interstitial Lung Disease: Key Recommendations from the 2026 International Working Group Report
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