Internal Medicine – Page 3

Deciphering the Link Between Postoperative Delirium, Rehospitalization, and Cognitive Decline in Older Adults

By MedXY 08/10/2026

This study investigates whether recurrent hospitalizations mediate the association of postoperative delirium with long-term cognitive decline in seniors after major surgery, finding that rehospitalization does not significantly affect this relationship.

Internal Medicine news Public Health

ACP 2026 Position Paper: A Policy Roadmap to Make Obesity Prevention and Treatment Affordable, Accessible, and Stigma-Free

By MedXY 08/07/2026

The American College of Physicians' 2026 position paper calls for comprehensive payer coverage, healthy food access, bias reduction, and research to tackle adult obesity through multisector public policy.

Internal Medicine news Public Health

Evaluating LACE and HOSPITAL Scores for Predicting 30-day Readmissions in a Pakistani Tertiary Care Setting

By MedXY 08/07/2026

A large retrospective study from Pakistan shows that LACE and HOSPITAL scores have fair accuracy in predicting 30-day readmissions among internal medicine patients, supporting their use in LMIC hospitals to target interventions and improve care outcomes.

Hematology-Oncology Internal Medicine news

Unveiling BPNT1 Mutations as a Novel Cause of Vitamin B12-Dependent Megaloblastic Anemia

By MedXY 08/07/2026

Biallelic loss-of-function mutations in BPNT1 are identified as a new genetic cause of vitamin B12-dependent megaloblastic anemia, linked to disrupted ribosome biogenesis and impaired ileal vitamin B12 absorption in mouse models.

Internal Medicine news

Enhancing Medical Education: Impact of a Structured Patient Discharge Curriculum on Student Competence and Patient Outcomes

By MedXY 08/05/2026

A structured discharge curriculum for sub-internship medical students significantly improves their discharge instruction skills and knowledge, positively influencing patient-reported understanding of urgent care instructions after hospital discharge.

Hematology-Oncology Internal Medicine news

Optimizing Outcomes in POEMS Syndrome: Real-World Insights on Autologous Stem Cell Transplantation from a Multicenter Study

By MedXY 08/05/2026

This multicenter study evaluates autologous stem cell transplantation (ASCT) in POEMS syndrome, showing significant hematologic response, durable survival, and manageable toxicity, highlighting ASCT's pivotal role in treatment.

Gastroenterology Internal Medicine news

Rapid Skeletal Muscle Loss in Cirrhosis: Predictors, Outcomes, and Implications for Clinical Management

By MedXY 08/04/2026

Rapid skeletal muscle loss occurs in a significant subset of cirrhosis patients and independently predicts waitlist mortality, highlighting sarcopenia as a critical therapeutic target in liver disease management.

Diabetes & Endocrinology Internal Medicine news

Metabolic Implications of Hepatic, Pancreatic, and Abdominal Fat Depots in Asian Indians Across Normoglycaemia, Prediabetes, and Type 2 Diabetes

By MedXY 08/03/2026

This study reveals that Asian Indians with prediabetes or type 2 diabetes show significantly higher liver and abdominal fat despite similar BMI, highlighting liver fat's key role in dysglycaemia and the importance of early intervention.

Diabetes & Endocrinology Internal Medicine news

Evaluating GLP-1 Receptor Agonists Versus Oral Agents for Insulin Discontinuation in Type 2 Diabetes: Insights from a Veterans Health Administration Target Trial Emulation

By MedXY 08/03/2026

A large study in veterans with type 2 diabetes found that adding GLP-1 receptor agonists to basal insulin did not improve insulin discontinuation rates compared to SGLT-2 inhibitors or DPP-4 inhibitors over three years.

Cardiology Internal Medicine news

Risk-Guided Screening for Atrial Fibrillation Using Electronic Health Records

By MedXY 07/30/2026

A machine learning model using electronic health records effectively identifies patients at high risk of atrial fibrillation, enabling targeted screening and early diagnosis to prevent stroke.

Cardiology Clinical Updates Internal Medicine news

Olorofim for Poorly Controlled Disseminated Coccidioidomycosis: Phase 2b Clinical Efficacy and Safety Insights

By MedXY 07/24/2026

This review synthesizes key findings evaluating olorofim's clinical effectiveness and safety in patients with refractory disseminated coccidioidomycosis, emphasizing its potential role amid limited treatment options.

Internal Medicine news Public Health

Predicting Opioid Use Disorder and Overdose Risk in Older Adults: Evaluating Prognostic Models

By MedXY 07/21/2026

This study develops and compares predictive models incorporating claims and patient-reported data to forecast time to first opioid use disorder (OUD) or overdose (OD) among older adults with chronic pain on opioids, identifying key risk factors for early intervention.

Internal Medicine news Public Health

Correlation Between Physicians’ Clinical Knowledge and Reduction of Low-Value Services in Older Adults

By MedXY 07/21/2026

Patients whose physicians demonstrate higher clinical knowledge are less likely to receive low-value healthcare services, reducing unnecessary medical spending and optimizing care quality in elderly Medicare beneficiaries.

Internal Medicine news Public Health

ACP Calls for Overhaul of U.S. Dietary Supplement Rules: Key Recommendations from the 2026 Position Paper

By MedXY 07/21/2026

The American College of Physicians urges Congress and regulators to modernize DSHEA, require premarket FDA review, strengthen surveillance, standardize labeling, and improve clinician tools to protect the public from unsafe or misleading dietary supplements.

Gastroenterology Internal Medicine news

Polypharmacy Challenges in Older Adults with Metabolic Dysfunction-Associated Steatotic Liver Disease: Navigating Care in a High-Risk Population

By MedXY 07/17/2026

Older adults with MASLD, especially those aged 75 and above, experience a high burden of polypharmacy linked to multimorbidity, necessitating careful medication management to balance disease control and geriatric vulnerabilities.

Gastroenterology Internal Medicine news

Global Variability in Non-Invasive Testing Accuracy for MASLD: Key Findings from the G-MASLD Study

By MedXY 07/16/2026

The G-MASLD study evaluated the diagnostic accuracy of non-invasive fibrosis tests across 41 countries, revealing regional variability and identifying Agile-3+ and Agile-4 as the most accurate for advanced fibrosis and cirrhosis in MASLD patients.

Clinical Updates Internal Medicine news

Mosaic Loss of Y Chromosome Links to Pulmonary Decline, Emphysema, and Accelerated Epigenetic Aging in Men: A Comprehensive Review

By MedXY 07/15/2026

Mosaic loss of Y chromosome (mLOY) in men is strongly associated with diminished lung function, increased emphysema severity, and faster epigenetic aging, positioning mLOY as a novel biomarker for respiratory aging and COPD risk in males.

Diabetes & Endocrinology Internal Medicine news

Next-Generation Pharmacotherapies in Obesity: Transforming Care with Precision and Multisystem Benefits

By MedXY 07/14/2026

Emerging obesity pharmacotherapies targeting entero-pancreatic hormones deliver substantial weight loss and improve multiple obesity-related complications, heralding a treat-to-target paradigm in obesity management with personalized, complication-centric care.

Gastroenterology Internal Medicine news

Unraveling IBS Genetics: Insights into Cardiometabolic and Triglyceride-Linked Mechanisms from a Large GWAS Meta-Analysis

By MedXY 07/13/2026

A genome-wide meta-analysis of 2.8 million individuals reveals genetic links between irritable bowel syndrome, brain-gut pathways, and cardiometabolic traits, highlighting novel therapeutic targets involving triglyceride metabolism.

Critical Care Internal Medicine news

Evaluating the ABCDEF Bundle in Australian ICUs: Impacts on Delirium, Functional Status, and Long-Term Quality of Life

By MedXY 07/12/2026

A pragmatic RCT in an Australian ICU found the ABCDEF bundle did not reduce delirium incidence or duration but improved patients' ability to perform usual activities at 90 days post-discharge, suggesting possible long-term quality of life benefits warranting further study.