Internal Medicine – Page 6

Higher Interleukin-6 Levels Predict Broad Cardiovascular Risk and Mortality Across Diverse Cohorts

By MedXY 05/31/2026

A pooled analysis of 59,396 participants found that higher serum IL-6 concentrations independently predicted nine cardiovascular and mortality outcomes, with consistent associations across key clinical subgroups.

Internal Medicine news Public Health

VA Health Professions Trainees Were Disrupted by COVID-19 but Became Meaningful Contributors to Clinical Care, Telehealth, and System Response

By MedXY 05/30/2026

A qualitative VA study found that COVID-19 reduced trainee learning opportunities and heightened safety concerns, yet trainees contributed substantially to care delivery, telehealth expansion, patient support, and local pandemic planning.

Internal Medicine news Public Health

Medicare Advantage Enforcement Has Been Inconsistent and Financially Modest Despite Expanding Federal Exposure

By MedXY 05/30/2026

A 2010-2023 analysis found that CMS enforcement against Medicare Advantage plans was highly variable, usually limited to modest monetary penalties, and more common among lower-rated contracts serving more socially vulnerable beneficiaries.

Diabetes & Endocrinology Internal Medicine news

Two-Year SURPASS-EARLY Findings Show Tirzepatide Outperforms Intensified Conventional Care in Early Type 2 Diabetes

By MedXY 05/30/2026

In adults with early type 2 diabetes inadequately controlled on metformin, tirzepatide produced greater 2-year reductions in HbA1c, body weight, and waist circumference than intensified conventional care, with substantially higher rates of normoglycemia.

Critical Care Internal Medicine news

Frequent Pre-Admission Ambulatory Visits May Flag Harmful Diagnostic Error Risk in High-Risk General Medicine Inpatients

By MedXY 05/27/2026

In a retrospective cohort of high-risk medical inpatients, frequent ambulatory care use before admission emerged as a predictor of harmful diagnostic error, highlighting a potentially actionable EHR-based signal for hospital diagnostic safety programs.

Gastroenterology Internal Medicine news

Metabolic Dysfunction Did Not Worsen Short-Term Survival in Severe Alcohol-Associated Hepatitis in a Global Prospective Cohort

By MedXY 05/26/2026

In a 32-center international cohort, cardiometabolic risk factors were common in alcohol-associated hepatitis but did not independently increase 180-day mortality after adjustment for liver disease severity and competing transplant risk.

Cardiology Internal Medicine news

Higher Lipoprotein(a) Marks Greater Coronary Risk Without Prior MI or Stroke, While Evolocumab Delivers Similar Relative Benefit and Larger Absolute Gains

By MedXY 05/25/2026

In VESALIUS-CV, elevated baseline Lp(a) independently predicted major coronary events, especially MI, in patients without prior MI or stroke. Evolocumab reduced relative risk similarly across Lp(a) levels, with numerically greater absolute benefit in those with higher Lp(a).

Critical Care Internal Medicine news

ICU Readmission Raises 60-Day Mortality Substantially Regardless of Frailty, but Frail Patients Carry the Highest Absolute Risk

By MedXY 05/22/2026

In a binational registry study of 615,719 ICU admissions, ICU readmission was linked to a similar absolute increase in 60-day mortality in frail and nonfrail patients, although frail readmitted patients had the highest overall mortality.

Internal Medicine news Public Health

ACP Calls for Stronger Oversight of Medicare Advantage to Protect Patients, Payment Accuracy, and Quality

By MedXY 05/22/2026

The American College of Physicians urges major reforms to Medicare Advantage, including more accurate payment, simpler quality measures, tighter oversight of marketing and prior authorization, and stronger transparency to better protect beneficiaries.

Internal Medicine news Respiratory

Effectiveness of Automatically-Adjusted vs Manually-Adjusted Noninvasive Ventilation in Obesity Hypoventilation Syndrome: A Randomized Clinical Trial

By MedXY 05/21/2026

In ambulatory patients with obesity hypoventilation syndrome, automatically-adjusted noninvasive ventilation was as effective as manually adjusted NIV over 12 months and more cost-effective, offering a simpler path to treatment.

General Surgery Internal Medicine news Otorhinolaryngology

Fatigue After Thyroidectomy: What Patients Actually Experience

By MedXY 05/20/2026

A qualitative study found that fatigue after thyroidectomy is common, disruptive, and often unexpected. Patients described major impacts on work and daily life, and many wanted surgeons to warn them about it before surgery.

Internal Medicine news Public Health

Telemedicine After the Pandemic: Who Benefits, What Changed, and What Comes Next

By MedXY 05/18/2026

Telemedicine is no longer an emergency workaround. New policy guidance shows how virtual care can improve access, but only if payment, safety, equity, and prescribing rules evolve carefully.

Cardiology Internal Medicine news

Cardiomyopathy Gene Therapy Reaches an Inflection Point: From AAV Delivery to Precision Genome Editing

By MedXY 05/12/2026

Gene therapy for cardiomyopathy is moving from concept to clinic, but durable benefit will depend on solving delivery, immunogenicity, cargo, and safety barriers in the failing human heart.

Cardiology Internal Medicine news

Sacubitril/Valsartan Improved Exercise Pulmonary Hemodynamics and Dynamic Atrial Functional Mitral Regurgitation in HFpEF: Interpreting the PRAISE-MR Randomized Trial

By MedXY 05/12/2026

In symptomatic HFpEF with atrial functional mitral regurgitation, sacubitril/valsartan improved exercise hemodynamics, peak VO2, symptoms, biomarkers, and stress-induced MR burden over 6 months versus standard care.

Internal Medicine news Psychiatry

Initiation of Medications for Alcohol Use Disorder Among Hospitalized Veterans : A Retrospective Cohort Study

By MedXY 05/11/2026

VHA study reveals only 30% of veterans hospitalized for AUD receive evidence-based medications during or shortly after hospitalization, with significant variation across hospitals and demographic factors influencing prescription rates.

Gastroenterology Internal Medicine news

低剂量聚乙二醇用于住院患者肠道准备的有效性：一项多中心随机试验

By MedXY 05/09/2026

意大利多中心研究发现，1升聚乙二醇抗坏血酸方案在住院患者结肠镜检查前肠道准备中，高质量清洁率显著优于2升和4升方案，且患者耐受性更好。

Diabetes & Endocrinology Internal Medicine news

甲状腺功能随年龄变化的自然历程：一项涵盖31项前瞻性队列研究的13.7万参与者个体数据分析

By MedXY 05/06/2026

大规模国际研究发现甲状腺功能随年龄变化存在性别和碘状态差异。虽然多数人甲状腺功能稳定且TSH轻微升高，但任何变化模式均与全因死亡风险增加1.8-2.5倍相关，这对老年甲状腺健康管理具有重要临床意义。

Cardiology Internal Medicine news

Targeting Skeletal Muscle Myosin ATPase May Reduce Resting Energy Waste in Heart Failure With Reduced Ejection Fraction

By MedXY 05/06/2026

An ex vivo human skeletal muscle study suggests that myosin ATPase inhibition with mavacamten normalizes excessive resting ATP consumption in HFrEF myofibres, identifying a mechanistically novel strategy to address peripheral metabolic inefficiency and exercise intolerance.

Cardiology Internal Medicine news

Long-Term SAFE-PAD Data Reassure on Mortality After Paclitaxel-Coated Femoropopliteal Interventions

By MedXY 05/06/2026

In Medicare patients undergoing femoropopliteal revascularization, drug-coated devices were not associated with higher long-term mortality, supporting the safety of paclitaxel-coated technology after years of regulatory concern.

Cardiology Internal Medicine news

PCSK9 Inhibition Lowers LDL Cholesterol in Heterozygous Familial Hypercholesterolemia Regardless of LDL Receptor Variant Function

By MedXY 05/03/2026

In a pooled nonrandomized phase 3 analysis, monthly lerodalcibep reduced LDL-C by about 50% in heterozygous familial hypercholesterolemia, with similar efficacy across LDLR functional variant categories and broad attainment of guideline-based LDL-C goals.