Critical Care – Page 2

Differential Ventilatory Strategies and Outcomes in Neurocritical Versus Non-Neurocritical Care Patients: Insights From the PRIME Database

By MedXY 10/26/2026

A pooled analysis from the PRIME database reveals distinct ventilatory management patterns and ARDS incidence in neurocritical versus non-neurocritical patients, highlighting key associations between ventilator settings and outcomes.

远程重症监护能力与重症 Medicare 患者跨院转运及潜在低价值转运的关联：全国性证据综合

Clinical Updates Critical Care news

Association of Tele-Critical Care Capability With Interhospital Transfers and Potentially Low-Value Transfers Among Critically Ill Medicare Beneficiaries: A Nationwide Evidence Synthesis

By MedXY 10/25/2026

This review synthesizes evidence linking tele-critical care with interhospital transfer patterns and outcomes, highlighting improved transfer selection and reduced low-value transfers among critically ill Medicare patients.

Cardiology Critical Care news

Unraveling sST2’s Role in Fulminant Myocarditis: A Novel Mitochondrial Therapeutic Axis

By MedXY 10/25/2026

Elevated soluble ST2 worsens fulminant myocarditis by impairing cardiomyocyte mitochondria via IGF2R-YY1, providing a new prognostic biomarker and therapeutic target.

Critical Care Nephrology news

Intermittent vs Continuous Renal-Replacement Therapy in Acute Kidney Injury: Insights from a Multicenter Trial

By MedXY 10/25/2026

This randomized trial compared intermittent hemodialysis and continuous renal-replacement therapy in critically ill AKI patients and found that continuous therapy was associated with lower 90-day mortality and similar kidney outcomes.

Critical Care Hematology-Oncology news

Heightened Risk of ICU-Acquired Infections in Hematological and Immunosuppressed Cancer Patients: Insights from a Large Brazilian Cohort

By MedXY 10/24/2026

A large nationwide cohort study reveals that patients with hematological malignancies and other immunosuppressive conditions have significantly higher risks of ICU-acquired infections, while those with solid tumors do not show increased incidence compared to non-immunosuppressed patients.

术中联用多巴酚丁胺与去甲肾上腺素可显著降低脓毒性休克术后急性肾损伤：来自多中心随机试验的证据

Critical Care Nephrology news

Intraoperative Dobutamine Plus Norepinephrine Significantly Reduces Postoperative Acute Kidney Injury in Septic Shock: Insights from a Multicenter Randomized Trial

By MedXY 10/23/2026

A randomized clinical trial demonstrates that adding intraoperative dobutamine to norepinephrine during surgical source control for septic shock significantly decreases postoperative acute kidney injury incidence and severity.

Critical Care Emergency Medicine news

Predicting Outcomes in Acutely Intoxicated ICU Patients: Integrating Toxicity Scores and Laboratory Data

By MedXY 10/23/2026

This study develops and evaluates prognostic models combining clinical and toxicity information to predict complicated outcomes in ICU patients with acute intoxication, demonstrating the added value of laboratory data over toxicity scores alone.

自动监测气管导管套囊压力可降低儿科ICU呼吸机相关性肺炎：一项高质量随机对照试验的新证据

Critical Care news Pediatrics

Continuous Automatic Endotracheal Cuff Pressure Monitoring Reduces Ventilator-Associated Pneumonia in Pediatric ICU: New Evidence from a Robust RCT

By MedXY 10/23/2026

Continuous automatic cuff pressure monitoring significantly lowers ventilator-associated pneumonia incidence in critically ill children by ensuring better pressure control, offering an effective preventive strategy in pediatric intensive care.

机械取栓术中的辅助性全身低温治疗：基于ReCCLAIM II试验的可行性与临床启示

Critical Care Neurology news

Adjuvant Systemic Hypothermia During Mechanical Thrombectomy: Feasibility and Clinical Insights from the ReCCLAIM II Trial

By MedXY 10/22/2026

The ReCCLAIM II trial demonstrates that rapid systemic hypothermia during mechanical thrombectomy for large-vessel occlusion stroke is feasible without delaying reperfusion, showing trends toward reduced infarct volume but raising safety considerations.

Critical Care news Respiratory

Optimizing Weaning Strategies from High-Flow Nasal Cannula in Critically Ill Adults: Insights from a Multicenter Randomized Trial

By MedXY 10/22/2026

A randomized clinical trial compared three high-flow nasal cannula weaning protocols in critically ill adults, finding no significant differences in success rates or weaning duration across flow reduction, FiO2 reduction, and simultaneous reduction strategies.

短いほどよいことも多い：敗血症とICU重症感染症における抗菌薬投与期間の専門家コンセンサス

Critical Care Infectious Diseases news

Shorter Is Often Better: Expert Consensus on Antibiotic Duration in Sepsis and Severe Infections in the ICU

By MedXY 10/22/2026

A 2026 expert consensus recommends shorter, individualized antibiotic courses for most severe infections in critically ill patients, with clear exceptions and guidance on biomarkers, source control, and stewardship.

12,13-diHOME：心搏骤停后靶向体温管理中棕色脂肪激活与预后的潜在标志物

Critical Care Diabetes & Endocrinology news

12,13-diHOME Levels as a Marker of Brown Adipose Tissue Activation and Outcome in Targeted Temperature Management Post-Cardiac Arrest

By MedXY 10/21/2026

This study reveals that elevated 12,13-diHOME levels, reflecting brown adipose tissue activation during targeted temperature management after cardiac arrest, correlate with improved survival and distinct immunometabolic profiles.

Critical Care news Respiratory

Integrated Respiratory and Functional Training Enhances Weaning and Recovery After Emergency Abdominal Surgery: Insights from a Randomized Controlled Trial

By MedXY 10/21/2026

This RCT demonstrates that combining multidimensional functional training with inspiratory muscle training and chest physiotherapy improves weaning success, muscle strength, functional independence, pain reduction, and ICU stay following emergency abdominal surgery.

Critical Care news Nursing & care

Implementing a Provincial Web-Based Family Satisfaction Survey in ICUs: Insights from Ontario’s Quality Improvement Initiative

By MedXY 10/20/2026

A province-wide quality improvement initiative in Ontario implemented a web-based Family Satisfaction in ICU (FS-ICU) survey across adult level 3 ICUs, revealing high satisfaction scores yet highlighting challenges in participation and completion that inform future patient- and family-centered care improvements.

心原性ショックにおける一時的機械的循環補助：2026年EAPCI–ACVCコンセンサスの重要推奨

Cardiology Critical Care news

Temporary Mechanical Circulatory Support in Cardiogenic Shock: Key Recommendations from the 2026 EAPCI–ACVC Consensus

By MedXY 10/19/2026

The 2026 EAPCI–ACVC consensus refines use of temporary mechanical circulatory support in acute myocardial infarction with cardiogenic shock, emphasizing phenotype-driven device selection, SCAI/SHARC staging, multidisciplinary shock teams and regionalized systems to improve outcomes.

急性低酸素性呼吸不全に対するイソフルラン吸入鎮静：SAVE-ICUランダム化臨床試験から得られた知見

Clinical Updates Critical Care news Respiratory

Isoflurane-Based Inhaled Sedation for Acute Hypoxemic Respiratory Failure: Insights from the SAVE-ICU Randomized Clinical Trial

By MedXY 10/19/2026

This review critically examines the SAVE-ICU trial assessing isoflurane inhaled sedation versus intravenous sedation in mechanically ventilated adults with acute hypoxemic respiratory failure, highlighting implications for clinical practice and future research needs.

Clinical Updates Critical Care news Pediatrics

Evaluation of a Commercial Pediatric Sepsis Early Detection Alert in Emergency Departments: Efficacy, Equity, and Clinical Implications

By MedXY 10/19/2026

This review synthesizes evidence evaluating the Epic Pediatric Sepsis Early Detection Model (PESM), highlighting its low sensitivity for early sepsis identification, disparities in performance across demographics, and implications for clinical practice and future screening tool development.

Critical Care news Respiratory

Impact of Prioritization on Severe Primary Graft Dysfunction After Lung Transplantation: Disentangling Risk Factors and Outcomes

By MedXY 10/19/2026

Prioritized lung transplant recipients exhibit higher severe PGD rates and mortality, yet prioritization itself is not an independent PGD predictor; pre-transplant ECMO is the primary risk factor.

Critical Care Nephrology news

Reevaluating Oliguria Thresholds in Critical Care: Implications for AKI, CKD, and Mortality Risk

By MedXY 10/19/2026

New evidence suggests lower urine output thresholds than current standards better predict acute kidney injury, chronic kidney disease, and mortality in critically ill patients, urging redefinition of oliguria parameters in AKI diagnostics.

急性呼吸不全における気管支分泌物過剰への高頻度胸壁振動療法：エビデンスの整理と臨床的意義

Clinical Updates Critical Care news Respiratory

High-Frequency Chest Wall Oscillation in Acute Respiratory Failure With Bronchial Hypersecretion: Evidence Synthesis and Clinical Implications

By MedXY 10/19/2026

This review synthesizes current evidence on high-frequency chest wall oscillation (HFCWO) for airway clearance in acute respiratory failure with bronchial hypersecretion, highlighting recent RCT findings, mechanistic insights, and future research priorities.