Critical Care – Page 3

Reevaluating Ventilation Rates During Pediatric CPR: New Insights into Age-Stratified Outcomes

By MedXY 10/18/2026

This article explores findings from a multicenter study evaluating the impact of cardiopulmonary resuscitation ventilation rates on survival in pediatric intensive care, identifying age-specific ventilation targets linked to improved outcomes.

Critical Care news Rehabilitation Medicine

Assessing Muscle Recovery: Responsiveness of the K-Force Grip Dynamometer in ICU-Acquired Weakness Patients

By MedXY 10/17/2026

This study confirms the K-Force grip dynamometer as a responsive tool to detect short-term changes in handgrip strength in ICU-acquired weakness patients, supporting its clinical utility in critical care rehabilitation.

Cardiology Critical Care news

Impact of Prolonged Inotropic Use on Outcomes During VA ECMO Support in Cardiogenic Shock

By MedXY 10/17/2026

Higher cumulative inotropic exposure during VA ECMO support in cardiogenic shock is associated with increased risk of ECMO weaning failure, mortality, arrhythmias, and delayed lactate clearance, highlighting the need for prospective trials to optimize inotropic strategies.

Critical Care news Pediatrics

An Infant With Extreme Hypernatremia Treated With Peritoneal Dialysis

By MedXY 10/16/2026

A 34-day-old male infant with serum sodium >200 mmol/L from accidental salt ingestion was successfully treated with peritoneal dialysis, leading to full recovery.

Critical Care Diabetes & Endocrinology news

Impact of Diabetes and Atherosclerotic Cardiovascular Disease on the Prognostic Role of sTNFR1 in Sepsis Mortality

By MedXY 10/16/2026

This study reveals how diabetes and ASCVD alter the link between soluble TNF receptor 1 levels and 90-day sepsis mortality, informing biomarker-guided risk assessment and understanding of sepsis pathobiology.

Critical Care Emergency Medicine news

Optimizing Early Resuscitation in Septic Shock: Balancing Fluids and Vasopressors

By MedXY 10/16/2026

A large randomized trial finds no difference in 90-day days alive and out of hospital between early vasopressors with restricted fluids versus higher fluids with delayed vasopressors in septic shock, though pulmonary edema was less frequent with early vasopressors.

Critical Care news Respiratory

Validating the Patient Dignity Inventory to Enhance Recovery in Acute Respiratory Failure Survivors

By MedXY 10/15/2026

This study validates the Patient Dignity Inventory (PDI) as a reliable tool to assess dignity-related distress over 12 months in acute respiratory failure survivors, supporting dignity-centered interventions to improve long-term psychosocial outcomes.

Clinical Updates Critical Care news Respiratory

Modulation of Respiratory Drive by Ondansetron in Acute Respiratory Distress Syndrome: Emerging Evidence and Clinical Implications

By MedXY 10/14/2026

Ondansetron, a 5-HT3 antagonist, reduces respiratory drive in ARDS patients on mechanical ventilation by attenuating pulmonary C-fiber mediated stimulation, potentially lessening lung injury and improving oxygenation.

Critical Care news Pediatrics

Optimizing Care for Neonates with Transient Tachypnea: Strategies to Reduce NICU Length of Stay and Interventions

By MedXY 10/13/2026

Standardizing care for neonates with transient tachypnea significantly reduced NICU length of stay and medical interventions without compromising safety or breastfeeding rates.

Critical Care news Public Health

Racial and Ethnic Disparities in Physical Impairment Among ICU Survivors: Implications for Post-Hospital Care

By MedXY 10/13/2026

Non-Hispanic Black and Hispanic ICU survivors exhibit higher rates of physical impairment at discharge and increased healthcare utilization within one year, highlighting critical racial and ethnic disparities in post-ICU recovery.

Clinical Updates Critical Care Infectious Diseases news

Individualized Treatment Effects of Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized with Acute Infection: A Review of Evidence and Clinical Implications

By MedXY 10/13/2026

This review synthesizes evidence on how individual patient characteristics modify the comparative effects of cefepime versus piperacillin-tazobactam on acute kidney injury and neurologic outcomes in adults hospitalized with acute infection.

Critical Care news

Optimizing ICU Pharmacist Workload: Impact on Patient Mortality and Medication Management

By MedXY 10/11/2026

This study identifies higher pharmacist-to-patient ratios and interruptions in comprehensive medication management as key contributors to increased mortality among ICU patients, highlighting the need for optimized pharmacist staffing in critical care.

Cardiology Critical Care news

In-Hospital Cardiac Arrest in China: Incidence, Care Processes, and Survival Outcomes in a Multicenter Prospective Study

By MedXY 10/10/2026

This multicenter Chinese registry study reveals a high incidence of in-hospital cardiac arrest with low survival rates and highlights critical gaps in postresuscitation care and systemic factors limiting outcomes.

Critical Care Infectious Diseases news

White Blood Cell Count as a Predictor of Antibiotic Efficacy in Sepsis: Insights from Comparative Studies of Cefepime and Piperacillin-Tazobactam

By MedXY 10/09/2026

White blood cell count modifies mortality outcomes in sepsis patients treated with cefepime versus piperacillin-tazobactam, suggesting its potential role in guiding antibiotic selection.

Critical Care news Respiratory

TISA-818 in ARDS Due to Pulmonary Infection: Promising Safety and Early Efficacy Signals with the 2023 Global Definition

By MedXY 10/08/2026

A phase 2 randomized trial shows that TISA-818, an anti-inflammatory montelukast-decapeptide conjugate, is safe and may improve respiratory outcomes in ARDS patients, especially non-intubated individuals, supporting larger trials.

Critical Care Neurology news

Evolving Patterns in Withdrawal of Life-Sustaining Treatment Among Traumatic Brain Injury Patients: Insights From a Decade of ACS Trauma Data

By MedXY 10/05/2026

A decade-long analysis reveals a modest decline and delayed timing in withdrawal of life-sustaining treatment among patients with traumatic brain injury, highlighting evolving prognostic attitudes and clinical decision-making.

Clinical Updates Critical Care news Transplantation

Changing Brain Death Donation Dynamics in Spain: A National Overview of Neurocritical Care and Organ Donation Trends

By MedXY 10/02/2026

This review synthesizes national data from Spain (2015-2024) revealing a decline in brain death donation (DBD) offset by growth in controlled donation after circulatory death (cDCD), alongside evolving neurocritical care practices influencing organ donation pathways.

Critical Care Neurology news

Hospital Variation in Early Tracheostomy and Life-Sustaining Treatment Withdrawal in Severe TBI: Insights from a Nationwide Study

By MedXY 10/01/2026

This nationwide study reveals that hospitals with higher tendencies for early tracheostomy in severe TBI patients also show increased rates of withdrawal of life-sustaining treatment, highlighting significant practice variability and its potential impact on patient outcomes.

Critical Care news Nursing & care

Exploring ICU Staff Perspectives on Brain Death: Insights from a Swiss Multicenter Survey

By MedXY 10/01/2026

A Swiss study reveals ICU professionals' perceptions, knowledge, and ethical views on brain death, highlighting knowledge gaps and the positive impact of clinical experience on understanding.

Critical Care Infectious Diseases news

International Validation of Sepsis Temperature-Trajectory Subphenotypes Reveals Immune and Coagulation Profiles with Implications for Immunoglobulin Therapy

By MedXY 10/01/2026

This study validates temperature-trajectory sepsis subphenotypes in a large Chinese ICU cohort, linking immune and coagulation dysfunction with mortality and highlighting differential responses to immunoglobulin therapy, particularly benefit in hypothermic patients.