AI-Derived Panoramic Radiograph Score Links Oral Health to Major Systemic Diseases

Highlight

  • An AI model quantified alveolar bone loss and missing teeth from 26,550 panoramic radiographs to generate a continuous oral health score.
  • The AI-derived panoramic score was independently and inversely associated with five systemic diseases: diabetes mellitus, hypertension, osteoporosis, ischemic heart disease, and hyperlipidemia.
  • The score’s highest relative risk discrimination was for ischemic heart disease, and it showed incremental predictive value for diabetes, hypertension, and hyperlipidemia beyond age, sex, and BMI.
  • This approach offers an automated, quantitative, non-invasive imaging biomarker that could facilitate integrated dental and medical disease management.

Study Background

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