Challenges in Using Insulin Dose-Adjusted HbA1c to Identify Partial Remission in Pediatric Type 1 Diabetes: Insights from the SEARCH for Diabetes in Youth Study
Posted inDiabetes & Endocrinology news Pediatrics

Challenges in Using Insulin Dose-Adjusted HbA1c to Identify Partial Remission in Pediatric Type 1 Diabetes: Insights from the SEARCH for Diabetes in Youth Study

This study highlights the limitations of insulin dose-adjusted hemoglobin A1c (IDAA1c) ≤9 in detecting partial remission in US youth with type 1 diabetes, especially those with overweight or obesity, suggesting BMI-specific adjustments improve accuracy but reduce specificity.
Increased Risk of Obstructive Sleep Apnea and Poor Sleep Quality Among Older Adults With Type 1 Diabetes: Insights from the DCCT/EDIC Cohort
Posted inClinical Updates Diabetes & Endocrinology news Respiratory

Increased Risk of Obstructive Sleep Apnea and Poor Sleep Quality Among Older Adults With Type 1 Diabetes: Insights from the DCCT/EDIC Cohort

This review synthesizes evidence from the DCCT/EDIC study highlighting the high prevalence and risk factors of obstructive sleep apnea and poor sleep quality in older adults with long-standing type 1 diabetes, emphasizing the clinical and mechanistic implications for patient management.
Immunogenicity up to Age 5 Following Single- or Two-Dose Infant Primary Series of 10-Valent and 13-Valent Pneumococcal Conjugate Vaccine with Booster in South Africa: Extended RCT Follow-Up
Posted inClinical Updates news Pediatrics Public Health

Immunogenicity up to Age 5 Following Single- or Two-Dose Infant Primary Series of 10-Valent and 13-Valent Pneumococcal Conjugate Vaccine with Booster in South Africa: Extended RCT Follow-Up

This review synthesizes long-term immunogenicity data from a South African RCT comparing 1+1 and 2+1 infant PCV10 and PCV13 schedules. PCV13 1+1 schedules maintain durable immunity up to age 5, supporting schedule optimization in established programs.