HPV-Associated Anal Dysplasia in Solid Organ Transplant Recipients: Unraveling Transplant-Specific Mucosal Immune Dysfunction
Posted inInfectious Diseases news Oncology

HPV-Associated Anal Dysplasia in Solid Organ Transplant Recipients: Unraveling Transplant-Specific Mucosal Immune Dysfunction

Solid organ transplant recipients have increased risk of HPV-driven anal dysplasia and cancer due to unique immune alterations from immunosuppression. This article explores the transplant-specific immune dysfunction underlying persistent HPV infection and dysplastic progression, highlighting implications for screening and management.
HPV-Associated Anal Dysplasia in Solid Organ Transplant Recipients: Exploring Transplant-Specific Mucosal Immune Dysregulation
Posted inInfectious Diseases news Oncology Transplantation

HPV-Associated Anal Dysplasia in Solid Organ Transplant Recipients: Exploring Transplant-Specific Mucosal Immune Dysregulation

Solid organ transplant recipients exhibit heightened risk for HPV-associated anal dysplasia and cancer due to unique immunosuppressive alterations. A transplant-tailored model of mucosal immune dysfunction elucidates mechanisms driving persistent HPV infection and dysplasia progression, informing future screening and therapeutic strategies.
Why Hepatitis E Remains a Silent Threat in Transplant Recipients: Key Insights from Two Decades of Data
Posted inGastroenterology Infectious Diseases news Transplantation

Why Hepatitis E Remains a Silent Threat in Transplant Recipients: Key Insights from Two Decades of Data

A 20-year retrospective study of 6,452 solid organ transplant patients reveals hepatitis E infection rates of 3.5%, with chronicity rates exceeding 65%. The findings highlight the critical importance of HEV screening and the effectiveness of extended ribavirin therapy in achieving viral clearance.