myocardial injury

Metrnl: A Novel Inhibitor of Platelet Activation Targeting CD36 to Mitigate Thrombosis and Acute Myocardial Injury

By MedXY 08/21/2026

Metrnl reduces platelet activation and thrombus formation by promoting CD36 degradation, offering a promising therapeutic strategy for thrombotic diseases including acute myocardial infarction without increasing bleeding risk.

Cardiology news Pathology & Lab Medicine/Bệnh học

Why the cTnI/cTnT Ratio May Matter: A New Signal for Distinguishing Acute Necrotic From Chronic Myocardial Injury

By MedXY 05/12/2026

A large multicohort and experimental study suggests the cTnI/cTnT ratio is biologically informative, separates acute from chronic myocardial injury, and modestly improves type 1 versus type 2 MI discrimination.

Cardiology Diabetes & Endocrinology news

Beyond Insulin Resistance: Why Diabetes Status Dictates the Cardiovascular Risk of the Triglyceride-Glucose Index

By MedXY 12/24/2025

A prospective ARIC cohort study reveals that diabetes fundamentally modifies the relationship between the triglyceride-glucose (TyG) index and subclinical myocardial injury, shifting the risk profile from an L-shaped to a J-shaped association over a six-year follow-up.

Cardiology news Otorhinolaryngology

Myocardial Injury Is Common After Major Head and Neck Surgery and Predicts Early Mortality: Insights from the VISION Cohort

By MedXY 11/21/2025

A VISION cohort analysis found myocardial injury after major head and neck surgery (MINS) in 11.9% overall and 23.8% of patients ≥75, strongly associated with 30‑day mortality and longer hospital stay; most events were clinically silent without troponin monitoring.

Cardiology General Surgery news Specialties

Ivabradine Fails to Reduce Myocardial Injury After Noncardiac Surgery: Insights from a Large RCT

By MedXY 09/06/2025

A large randomized trial shows that ivabradine, despite effectively lowering heart rate during surgery, does not reduce myocardial injury after noncardiac surgery, highlighting the complexity of perioperative cardiac risk management.

Cardiology news Specialties

Periprocedural Myocardial Injury after Elective PCI: Incidence and Impact on Long-Term Mortality

By MedXY 08/17/2025

Post-PCI myocardial injury defined by elevated CKMB is common and linked to increased long-term mortality, with more complex coronary anatomy predicting the injury occurrence.