Beyond Insulin Resistance: Why Diabetes Status Dictates the Cardiovascular Risk of the Triglyceride-Glucose Index

Highlights

The Triglyceride-Glucose (TyG) index, a reliable surrogate for insulin resistance, shows a complex, non-linear relationship with subclinical myocardial injury (SCMI) in the general population.

The association between TyG and myocardial injury is not universal; it is significantly modified by the presence of diabetes, which transforms the risk trajectory from L-shaped to J-shaped.

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