MRI biomarkers – Medxy AI

MRI-Derived EOAD-Signature Atrophy as a Prognostic Biomarker in Early-Onset Mild Cognitive Impairment

By MedXY 08/28/2026

Baseline cortical atrophy within an EOAD-specific brain signature predicts progression from mild cognitive impairment to dementia, providing a valuable MRI biomarker for individualized prognosis in early-onset Alzheimer disease.

Clinical Updates news

Clinical Implications of Hyperintense Reperfusion Marker and Ocular Gadolinium Leakage Post-Thrombectomy: Insights from the ETIS Registry

By MedXY 08/25/2026

This review elucidates the prognostic significance of HARM and GLOS as imaging biomarkers after mechanical thrombectomy, highlighting their associations with early neurological outcomes and infarct progression.

Neurology news

Paramagnetic Rim Lesions as Predictors of Progression in Multiple Sclerosis: Insights from a 5-Year Longitudinal Study

By MedXY 08/22/2026

Paramagnetic rim lesions detected via MRI are associated with increased risk of disability progression independent of relapse activity and accelerated brain atrophy in multiple sclerosis, highlighting their role as prognostic biomarkers for risk stratification.

Cardiology Neurology news

Validating VasCog-2-WSO Criteria: Early MRI Detection of Vascular Cognitive Impairment and Mortality Risk in Stroke- and Dementia-Free Adults

By MedXY 08/04/2026

The VasCog-2-WSO criteria effectively detect MRI-defined vascular cognitive impairment in asymptomatic adults, correlating with increased cardiovascular risk and mortality, highlighting their utility for early diagnosis and community risk stratification.

Neurology news Psychiatry

Familial Microvascular Traits and Neuropsychiatric Factors Reflected in Brain Perivascular Space Morphometry

By MedXY 07/20/2026

Brain perivascular space morphometry reveals familial microvascular architecture and neuropsychiatric influences, offering a novel imaging biomarker of cerebral microvascular health beyond traditional vascular risk factors.

Clinical Updates Neurology news Radiology

The Prognostic Significance of Paramagnetic Rim Lesions in Radiologically Isolated Syndrome: A New Paradigm for Early Multiple Sclerosis Diagnosis

By MedXY 03/10/2026

This review explores how paramagnetic rim lesions (PRLs), as markers of chronic active demyelination, serve as powerful predictors for clinical Multiple Sclerosis conversion in individuals with radiologically isolated syndrome.

news Orthopedics Radiology

T2 Mapping Detects BMI-Linked Cartilage Changes and Lateral Compartment Signal Differences in Population-Based Knee OA

By MedXY 11/02/2025

In a large population-based sample, cartilage T2 relaxation times correlated with BMI and were higher in knees with MRI-defined osteoarthritis, particularly in lateral cartilage subregions; T2 did not reflect patient-reported symptoms.