gut-brain axis – Medxy AI

Harnessing Kynurenic Acid and the Gut-Brain Axis to Improve Stroke Recovery

By MedXY 09/18/2026

Kynurenic acid (KYNA) reduction in the gut correlates with worse poststroke outcomes. Supplementation activates a gut-brain neural circuit via GPR35 and the vagus nerve, promoting neuroprotection and functional recovery after ischemic stroke.

Neurology news Pediatrics

Is the Gut Microbiome Really a Key to Understanding Autism?

By MedXY 11/13/2025

A critical review highlights serious flaws in research linking gut microbiome to autism, questioning its causal role and urging more rigorous studies or reconsideration of this research path.

Clinical Updates Neurology news Specialties

Microbiome Virulence Signatures in the Oral-Gut-Brain Axis: New Insights into Parkinson’s Disease and Cognitive Decline

By MedXY 09/29/2025

This study reveals how virulence factors in oral and gut microbiomes and their translocation affect cognitive impairment in Parkinson’s disease, highlighting novel biomarker potential and the importance of the oral-gut-brain axis for early diagnosis and therapeutic strategies.

Clinical Updates Family Medicine & Nutrition news Psychiatry Specialties

Enhancing Vagal Nerve Function with Multi-Species Probiotics: A Promising Therapeutic Avenue for Major Depression

By MedXY 09/17/2025

A 3-month RCT demonstrates that multi-species probiotic supplementation improves vagal nerve function, gut microbiome composition, and sleep quality in patients with major depression, suggesting novel gut-brain axis interventions.

Clinical Updates Neurology news Specialties

Unraveling the Gut–Brain Connection: Tau Propagation via the Vagus Nerve in Alzheimer’s Disease

By MedXY 09/04/2025

Recent research reveals that pathological tau can propagate from the brain to the colon through the vagal efferent pathway in Alzheimer's disease, supporting a novel brain-to-gut axis involvement in disease progression and gut function impairment.

Family Medicine & Nutrition news Specialties

The Gut’s Sixth Sense: How Your Microbiome Quietly Controls Appetite

By MedXY 08/31/2025

Recent research unveils a 'neurobiotic sense' in the gut that detects bacterial molecules and regulates feeding through the gut-brain axis, reshaping our understanding of appetite control.

Neurology Pediatrics Specialties Transplantation

Exploring Fecal Microbiota Transplantation for Autism Spectrum Disorder: Efficacy, Safety, and Future Directions

By MedXY 08/18/2025

Fecal microbiota transplantation (FMT) shows promise in improving gastrointestinal and behavioral symptoms in children with autism spectrum disorder (ASD), but further rigorous trials are needed to confirm its efficacy and optimize protocols.

Gastroenterology news

Gut Feeling: The Surprising Link Between Your Stomach and Your Mood

By MedXY 07/25/2025

Emerging science reveals how your gut and brain communicate, shaping not only digestion but also emotions and mental health.