Neurology – Page 9

When Does an ICP Crisis Really Count? BOOST II Raises Questions About Bedside Detection in Severe TBI

By MedXY 06/19/2026

A post hoc BOOST II analysis found that many bedside-labeled intracranial pressure crises were not confirmed by continuous electronic data, challenging current ICP episode definitions in severe traumatic brain injury.

Neurology news Ophthalmology

Retinal Microvascular Clues to Alzheimer Disease: What Swept-Source OCT Angiography Reveals About Neurovascular Dysfunction

By MedXY 06/19/2026

SS-OCTA identified retinal and choriocapillaris microvascular changes associated with cognitive status in Alzheimer disease, including thinner GCC in dementia and a biphasic CCFD pattern, suggesting a promising noninvasive biomarker platform.

Neurology news

A New Way to Measure Prodromal Synucleinopathy: What the PSRS Adds for RBD Clinical Trials

By MedXY 06/17/2026

The PSRS showed good-to-excellent reliability and moderate-to-strong construct validity in a large RBD cohort, supporting its use as a multidomain measure of prodromal synucleinopathy burden.

Neurology news Public Health

Brain Imaging Biomarkers and Cognitive Outcomes in a Multidomain Lifestyle Intervention: The POINTER Imaging Ancillary Study

By MedXY 06/17/2026

The POINTER Imaging study found no overall brain biomarker changes from a structured lifestyle intervention, but participants with lower baseline hippocampal volume showed greater cognitive benefit, suggesting imaging may help identify who responds best.

Cardiology Neurology news

Multiple Sclerosis Does Not Appear to Worsen In-Hospital Outcomes After Cardiovascular Surgery, but Routine Home Discharge Is Less Common

By MedXY 06/11/2026

A large US inpatient analysis found similar in-hospital mortality and complication rates after cardiovascular surgery in patients with and without multiple sclerosis, but patients with MS were less often discharged routinely home.

Emergency Medicine Neurology news

Ultra-Early Remote Ischemic Postconditioning After Thrombectomy Appears Safe but Does Not Improve 90-Day Stroke Recovery

By MedXY 06/10/2026

In the EnTRIPS randomized trial, ultra-early remote ischemic postconditioning after successful endovascular thrombectomy was safe but did not significantly improve 90-day functional independence in acute ischemic stroke.

Neurology news OB/GYN & Women’s Health

Postmenopausal Migraine Signals Higher Ischemic Stroke Risk, Not Hemorrhagic Stroke, in the Women’s Health Initiative

By MedXY 06/10/2026

In a large cohort of postmenopausal women, migraine history was associated with a modest increase in ischemic stroke risk over 20 years, while total and hemorrhagic stroke risks were not significantly elevated.

Cardiology Neurology news

Hypertension-Related High-Risk Features May Identify Which Patients With Cryptogenic Stroke Benefit From Apixaban Instead of Aspirin

By MedXY 06/10/2026

An exploratory ARCADIA analysis suggests that patients with cryptogenic stroke and atrial cardiopathy without severe hypertension-related features may derive greater benefit from apixaban than aspirin, whereas those with high-risk hypertensive features may not.

Neurology news Radiology

Wider Intracranial Arteries, Not Cranial Arterial Stenosis, Track With Lacunar Stroke and Cerebral Small-Vessel Disease

By MedXY 06/10/2026

In a prospective mild stroke cohort, cranial arterial stenosis was not linked to cSVD, whereas basilar dolichoectasia and wider intracranial arteries were strongly associated with lacunar stroke, higher cSVD burden, incident infarcts, and white matter lesion progression.

Neurology news

Identification of Genetic Modifiers of Autosomal Dominant Alzheimer’s Disease: A Genome-Wide Association Study

By MedXY 06/10/2026

A genome-wide study identified three genetic modifiers of autosomal dominant Alzheimer’s disease, linking them to disease risk, earlier onset, and biomarker changes involving amyloid, tau, TDP-43, and brain aging.

$Acute Brain Injury in New-Onset Refractory Status Epilepticus and Etiology-Defined Status Epilepticus$

Critical Care Neurology news

Acute Brain Injury in New-Onset Refractory Status Epilepticus and Etiology-Defined Status Epilepticus

By MedXY 06/10/2026

This study found that cryptogenic NORSE causes severe, rapidly rising neuroaxonal injury, measured by NfL, and that higher NfL predicts worse short-term outcome. S100B was not useful for distinguishing groups.

Cardiology Neurology news

Acute Cardiac CT Added to Stroke Imaging Detects Cardiac Thrombi in About 1 in 16 Patients and Outperforms Transthoracic Echocardiography

By MedXY 06/10/2026

In a 3919-patient individual-level meta-analysis, acute cardiac CT detected cardiac thrombi in 6.2% of ischemic stroke cases, exceeded transthoracic echocardiography yield, added modest imaging burden, and identified patients with worse 90-day outcomes.

Neurology news Public Health

Why Prevalence Is Rising Differently in Parkinson Disease, Multiple Sclerosis, and Motor Neuron Diseases

By MedXY 06/09/2026

A large Sweden-France analysis suggests rising MS prevalence is mainly survival-driven, increasing MND prevalence reflects growing incidence, and PD prevalence rises modestly through mixed demographic and survival effects.

Neurology news Radiology

Mechanical Thrombectomy and Final Infarct Volume in Medium or Distal Vessel Occlusion Stroke: A Post Hoc Analysis of a Randomized Clinical Trial

By MedXY 06/09/2026

In a post hoc analysis of the DISTAL trial, mechanical thrombectomy plus best medical treatment preserved more threatened brain tissue than medical treatment alone in medium or distal vessel occlusion stroke, and better tissue preservation was linked to improved 90-day outcomes.

Neurology news Radiology

Ultra-High-Resolution Photon-Counting CTA Improves Noninvasive Detection of Neurovascular In-Stent Restenosis

By MedXY 06/07/2026

A prospective study suggests ultra-high-resolution photon-counting CTA can detect neurovascular in-stent restenosis with excellent accuracy while reducing blooming artifacts and improving visualization of in-stent pathology.

Neurology news Pediatrics

Neurocognitive Outcomes of In Utero Exposure to Antiseizure Medication: An Australian Cohort Study

By MedXY 06/07/2026

An Australian cohort study found that prenatal exposure to valproate, levetiracetam, topiramate, and carbamazepine was associated with poorer cognitive outcomes in children, while lamotrigine exposure was not.

Neurology news Pathology & Lab Medicine/Bệnh học

A Two-Marker Plasma Model Closely Mirrors PET-Based Biological Staging of Alzheimer Disease

By MedXY 06/07/2026

Plasma %p-tau217 plus eMTBR-tau243 showed strong agreement with amyloid/tau PET staging, tracked clinical severity, and aligned with neuropathology, supporting a scalable blood-based approach to Alzheimer disease biological staging.

Neurology news OB/GYN & Women’s Health

Pregnancy Complications Signal Long-Term Maternal Risk of Subarachnoid Hemorrhage in a 50-Year Swedish Cohort

By MedXY 06/05/2026

In a nationwide Swedish cohort, several adverse pregnancy outcomes were linked to higher long-term maternal risk of subarachnoid hemorrhage, supporting pregnancy as an early vascular stress test.

Neurology news Public Health

Rural-Urban Disparities in Epilepsy Outcomes in the United States

By MedXY 06/05/2026

A national U.S. study found that patients with epilepsy from rural counties had worse hospital outcomes, including higher mortality, more status epilepticus, longer stays, and less EEG use, highlighting access-related disparities.

Neurology news Psychiatry

Ecopipam Reduced Relapse Risk in Pediatric Tourette Syndrome Without Metabolic or Extrapyramidal Signal in a Phase 3 Randomized Withdrawal Trial

By MedXY 06/05/2026

In a phase 3 randomized withdrawal trial, ecopipam maintained tic improvement in pediatric Tourette syndrome over 24 weeks and showed a generally favorable safety profile without clinically meaningful weight, metabolic, or drug-induced movement disorder effects.