Vitamin D – Medxy AI

Vitamin D Co-administration as a Protective Strategy Against Obesity-Induced Male Reproductive Dysfunction: Mechanistic Insights and Clinical Implications

By MedXY 03/02/2026

This review synthesizes recent evidence on how Vitamin D mitigates high-fat diet-induced testicular and sperm dysfunction, focusing on hormonal recovery, blood-testis barrier stabilization, and mitochondrial protection.

news

Vitamin D Supplementation Fails to Boost IVF Success in Women with PCOS: Results from the VitD-PCOS Trial

By MedXY 02/23/2026

A large-scale multicenter RCT reveals that while 4000 IU/day of Vitamin D significantly raises serum 25-OHD levels in women with PCOS, it does not improve live birth rates following the first embryo transfer in IVF cycles.

Allergy & Immunology news Pediatrics

High-Dose Prenatal Vitamin D and Childhood Atopy: Why Maternal Smoking History Matters

By MedXY 01/20/2026

Recent findings from the COPSAC2010 trial and EDEN cohort suggest that high-dose prenatal vitamin D's protective effect against atopic dermatitis is significantly enhanced in children of mothers exposed to tobacco, highlighting a potential personalized prevention strategy for high-risk pregnancies.

news Pediatrics

Targeted Bone Support: High-Dose Vitamin D and Calcium Improve Bone Mineral Density in Adolescents with HIV and Baseline Insufficiency

By MedXY 01/14/2026

The VITALITY trial reveals that while high-dose vitamin D and calcium supplementation did not benefit all adolescents with HIV, it significantly improved bone density in those with baseline vitamin D insufficiency, providing a safe strategy for optimizing peak bone mass.

Gastroenterology Internal Medicine news

Unraveling the Impact of Vitamin D Supplementation on Chronic Liver Disease: Insights from a Comprehensive Meta-Analysis

By MedXY 10/12/2025

Vitamin D supplementation in chronic liver disease modestly improves liver enzymes and insulin resistance, but shows no survival benefit or effects on liver stiffness and fat accumulation. Further large trials are needed to clarify its clinical role.

Clinical Updates Family Medicine & Nutrition news Specialties

Single high-dose Vitamin D Protect Bone Health During Extreme Ultramarathon Running

By MedXY 09/20/2025

A single high dose of vitamin D3 before ultramarathon running reduces post-exercise bone resorption and supports bone formation, suggesting vitamin D's potential to modulate bone health via calcium and parathyroid hormone regulation during extreme endurance events.

Family Medicine & Nutrition Specialties

Vitamin D and Cancer: Unveiling the Protective Role and Clinical Implications

By MedXY 08/18/2025

This article systematically reviews evidence linking vitamin D sufficiency to reduced cancer risk and mortality, underscores pitfalls in clinical trials, and outlines strategies for effective supplementation.