Atrial Mechanical Dysfunction as a Predictor of Stroke Risk in Transthyretin Amyloid Cardiomyopathy Patients in Sinus Rhythm
Posted inCardiology Neurology news

Atrial Mechanical Dysfunction as a Predictor of Stroke Risk in Transthyretin Amyloid Cardiomyopathy Patients in Sinus Rhythm

Left atrial mechanical dysfunction, particularly atrial electromechanical dissociation and impaired left atrial strain contraction, forecasts increased cerebrovascular events in transthyretin amyloid cardiomyopathy patients even in sinus rhythm, suggesting new stratification strategies for anticoagulation.
Acoramidis Shows Consistent Benefit in Wild‑Type and Variant Transthyretin Amyloid Cardiomyopathy — Signal Extends Through 42 Months
Posted inCardiology news

Acoramidis Shows Consistent Benefit in Wild‑Type and Variant Transthyretin Amyloid Cardiomyopathy — Signal Extends Through 42 Months

In ATTRibute‑CM and its open‑label extension, acoramidis (712 mg twice daily) produced consistent reductions in all‑cause mortality and cardiovascular hospitalizations in both wild‑type and variant ATTR cardiomyopathy, including p.Val142Ile, with mortality benefit persisting through month 42.