stroke prevention

Risk-Guided Screening for Atrial Fibrillation Using Electronic Health Records

By MedXY 07/30/2026

A machine learning model using electronic health records effectively identifies patients at high risk of atrial fibrillation, enabling targeted screening and early diagnosis to prevent stroke.

Cardiology Clinical Updates news

Temporal Trends in Oral Anticoagulant Use and Clinical Outcomes Among Older Adults with Atrial Fibrillation: Insights from a Danish Nationwide Study and Contemporary Evidence

By MedXY 07/16/2026

Recent decades saw increased anticoagulant use and reduced stroke risk in elderly AF patients, especially with DOACs, but bleeding risks rise notably in very elderly patients, highlighting tailored management needs.

Cardiology General Surgery news

Routine Surgical Left Atrial Appendage Occlusion Did Not Improve 1-Year Outcomes in Valvular Surgery Patients Without Atrial Fibrillation: Insights From the OPINION Trial

By MedXY 05/28/2026

In OPINION, prophylactic left atrial appendage occlusion during valve surgery did not significantly lower stroke, TIA, or cardiovascular death at 1 year in patients without pre-operative atrial fibrillation.

Clinical Updates Neurology news Rehabilitation Medicine

Integrated Strategies for Stroke Prevention and Management: From Evidence-Based Dietary Patterns to Systemic Adherence

By MedXY 04/08/2026

This review synthesizes recent evidence on the neuroprotective effects of healthy dietary patterns (Mediterranean, MIND), the synergistic impact of lifestyle and pharmacotherapy (GLP-1), and systemic advances in acute stroke care and secondary prevention.

Cardiology Neurology news

Long-Term Efficacy and Safety of Transcatheter Patent Foramen Ovale Closure: A 20-Year Follow-Up Study

By MedXY 03/09/2026

A 20-year follow-up study of 130 patients demonstrates that transcatheter PFO closure is highly effective in preventing recurrent strokes, though long-term antithrombotic therapy increases bleeding risks, particularly in women.

Cardiology Neurology news

Long-Term Clinical Outcomes After Patent Foramen Ovale (PFO) Closure: A 20-Year Follow-Up Study

By MedXY 02/27/2026

This article examines the 20-year safety and efficacy of transcatheter PFO closure in patients with paradoxical embolism, highlighting low recurrence rates but significant long-term bleeding risks associated with antithrombotic therapy.

Neurology news Radiology

Apixaban Shows No Increased Risk of MRI-Detected Intracranial Hemorrhage Compared to Aspirin in Atrial Cardiopathy

By MedXY 02/05/2026

An exploratory analysis from the ARCADIA-MRI substudy reveals that apixaban carries a similar risk of incident intracranial hemorrhages, microbleeds, and superficial siderosis compared to aspirin in patients with atrial cardiopathy and cryptogenic stroke.

Diabetes & Endocrinology Neurology news

High Insulin Resistance Blunts the Superiority of Ticagrelor Over Clopidogrel in Minor Stroke Patients with CYP2C19 Mutations

By MedXY 01/22/2026

A post hoc analysis of the CHANCE-2 trial suggests that the clinical benefit of ticagrelor over clopidogrel for secondary stroke prevention in CYP2C19 loss-of-function carriers is significantly attenuated in patients with high insulin resistance.

Cardiology Neurology news

Genetic Risk Profile Predicts Stroke Prevention Benefit From Continuous Atrial Fibrillation Screening: A Secondary Analysis of the LOOP Study

By MedXY 01/22/2026

A secondary analysis of the LOOP study demonstrates that continuous ECG screening with implantable loop recorders significantly reduces stroke and systemic embolism in individuals with high genetic risk for atrial fibrillation, while potentially increasing bleeding risk in lower-risk cohorts.

Neurology news Radiology

Drug-Coated Balloons Superior to Bare-Metal Stents in Preventing Restenosis for High-Grade Intracranial Atherosclerosis

By MedXY 01/21/2026

A multicenter randomized controlled trial demonstrates that drug-coated balloons significantly reduce 6-month restenosis and 1-year recurrent ischemic events compared to bare-metal stents in patients with symptomatic high-grade intracranial stenotic disease.

Neurology news Radiology

Drug-Coated Balloons Outperform Bare-Metal Stents in Reducing Restenosis for Symptomatic Intracranial Stenosis

By MedXY 01/21/2026

A multicenter RCT demonstrates that drug-coated balloon (DCB) angioplasty significantly reduces 6-month restenosis and 1-year recurrent ischemic events compared to bare-metal stenting in patients with high-grade symptomatic intracranial atherosclerotic disease.

Cardiology Internal Medicine news

Precision Medicine in Atrial Fibrillation: Biomarker-Based ABC-AF Risk Scores Fail to Outperform Standard Care

By MedXY 01/18/2026

A large-scale registry-based RCT reveals that tailoring atrial fibrillation treatment using the biomarker-driven ABC-AF risk score does not significantly reduce stroke or death compared to current standard guideline-based care, highlighting the complexities of implementing precision medicine in clinical practice.

Neurology news

Pushing the Limits: Very Low LDL-C Levels Below 40 mg/dL Proven Safe and Effective for Secondary Stroke Prevention

By MedXY 01/17/2026

A long-term analysis of the FOURIER trials reveals that achieving ultra-low LDL-C levels (<40 mg/dL) significantly reduces recurrent stroke and major cardiovascular events in stroke survivors, without increasing hemorrhagic stroke risk, supporting more aggressive lipid-lowering targets in clinical practice.

Cardiology Neurology news

Novel MicroNet-Covered Stent Sets New Safety Standard for High-Risk Carotid Artery Stenting: Insights from the C-GUARDIANS Trial

By MedXY 01/17/2026

The C-GUARDIANS trial reveals that the CGuard MicroNet-covered stent significantly reduces embolic risks in high-risk carotid artery stenting, achieving a remarkably low 30-day DSMI rate of 0.95% and sustained neuroprotection through one year.

Cardiology Neurology news

Distinct Neuroimaging Signatures: Atrial Fibrillation and Atherosclerosis Drive Divergent Vascular Brain Lesion Patterns

By MedXY 01/05/2026

A large-scale comparative study of 3,508 patients reveals that atrial fibrillation and atherosclerosis produce significantly different vascular brain lesions on MRI, with AF favoring non-lacunar infarcts and periventricular white matter changes, while atherosclerosis is linked to lacunar infarcts and micro-bleeds.

Cardiology Neurology news

Beyond Stenosis: Wall Shear Stress and Oscillatory Index Emerge as Key Biomarkers for High-Risk Carotid Plaques

By MedXY 01/02/2026

A study in Eur Heart J Cardiovasc Imaging identifies elevated systolic wall shear stress and low oscillatory shear index as independent predictors of complicated carotid artery plaques, offering a more precise framework for stroke risk stratification than traditional luminal narrowing assessments.

Neurology news Radiology

Circumferential Aneurysm Wall Enhancement Predicts a Three-Fold Increase in 4-Year Risk of Instability

By MedXY 01/02/2026

A large-scale prospective study in JAMA Neurology identifies circumferential aneurysm wall enhancement (AWE) as a potent independent predictor of intracranial aneurysm growth or rupture, offering a critical radiological biomarker for clinical risk stratification.

Cardiology Neurology news

CREST‑2: Stenting Reduces 4‑Year Ipsilateral Stroke vs Intensive Medical Therapy in Asymptomatic High‑Grade Carotid Stenosis; Endarterectomy Shows No Significant Benefit

By MedXY 11/21/2025

In CREST‑2, patients with ≥70% asymptomatic carotid stenosis randomized to carotid‑artery stenting plus intensive medical therapy had fewer perioperative-or-ipsilateral strokes over 4 years than intensive medical therapy alone; carotid endarterectomy did not show a statistically significant advantage.

Cardiology Neurology Orthopedics

Long-Term Outcomes of Extracranial Vertebral Artery Reconstruction in Managing Symptomatic Vertebral Artery In-Stent Restenosis or Occlusion

By MedXY 10/24/2025

This study evaluates the efficacy of vertebral artery reconstruction surgery versus medical therapy in reducing stroke recurrence and improving neurological outcomes over a ten-year period.

Cardiology news Public Health

Active Monitoring for Atrial Fibrillation (AMALFI): Advancing Long-Term Remote Screening to Reduce Stroke Risk

By MedXY 10/21/2025

The AMALFI trial evaluates remote screening for asymptomatic atrial fibrillation in older adults to improve detection, anticoagulation use, and reduce stroke risk, with findings pending follow-up at 2.5 and 5 years.