Endovascular Thrombectomy

Adjunct Intra-arterial Alteplase After Successful Basilar Thrombectomy Was Safe but Did Not Improve 90-Day Outcomes in IAT-TOP

By MedXY 05/10/2026

In the IAT-TOP randomized trial, intra-arterial alteplase after successful EVT for acute basilar artery occlusion did not improve 90-day functional independence, while symptomatic intracranial hemorrhage and mortality were similar between groups.

Neurology news

EVT Shows Superior Outcomes in Anterior Cerebral Artery Occlusion Stroke: Insights from the ORIENTAL-MeVO Registry

By MedXY 04/25/2026

Endovascular thrombectomy (EVT) significantly improves 90-day functional outcomes in acute anterior cerebral artery occlusion stroke compared to standard medical management, without increasing hemorrhage or mortality risks, per the ORIENTAL-MeVO Registry.

Neurology news Radiology

Even the Largest Stroke Cores May Benefit from Thrombectomy, LASTE Ancillary Analysis Suggests

By MedXY 04/19/2026

In patients aged under 80 with ASPECTS 0-2, endovascular thrombectomy improved disability outcomes and reduced mortality versus medical care alone, challenging the idea that very large infarcts should automatically exclude treatment.

Neurology news

Edaravone Dexborneol Improves Functional Recovery Following Endovascular Thrombectomy: Primary Results from the TASTE-2 Trial

By MedXY 01/21/2026

The multicenter TASTE-2 trial reveals that edaravone dexborneol significantly increases the likelihood of functional independence at 90 days for acute ischaemic stroke patients undergoing thrombectomy, particularly those presenting with a clinical-radiological mismatch, while maintaining a safety profile comparable to placebo.

Neurology news

Thrombectomy for Basilar Artery Occlusion: Sustained Efficacy and Survival Gains at Three Years

By MedXY 01/02/2026

The 3-year outcomes of the ATTENTION trial confirm that endovascular thrombectomy for acute basilar artery occlusion provides durable functional benefits and significantly reduces mortality compared to medical management, establishing its long-term superiority as the standard of care for younger and middle-aged patients.

AI Neurology news

AI-Driven Imaging Decision Support Doubles Thrombectomy Rates in Real-World Stroke Care

By MedXY 12/19/2025

A large-scale prospective study across England's NHS reveals that AI imaging software significantly boosts endovascular thrombectomy rates for acute stroke patients. Implementation was associated with a 100% relative increase in treatment at evaluation sites, highlighting AI's potential to bridge gaps in emergency neurointerventional care.

Neurology news

Bridging IV Alteplase Before EVT Modestly Raises Intracranial Hemorrhage Risk — But Net Clinical Impact Is Complex

By MedXY 12/11/2025

An IPD meta-analysis of six randomized trials (2313 patients) found IV alteplase before EVT modestly increased intracranial hemorrhage—particularly parenchymal hematoma—yet ICH risk must be balanced against IVT-associated improvements in reperfusion and potential clinical benefit.

Neurology news

IV Thrombolysis Outperformed Endovascular Thrombectomy for Basilar Artery Occlusion in a Multicenter Cohort: What Clinicians Should Know

By MedXY 12/07/2025

A 523‑patient multicenter cohort found intravenous thrombolysis alone was associated with better 3‑month functional outcomes and lower mortality than endovascular thrombectomy (± IVT) for acute basilar artery occlusion after adjustment for confounders. Results prompt cautious reappraisal of EVT vs IVT in BAO and call for randomized trials.

Neurology Specialties

Evaluating Intra-Arterial Tenecteplase Post-Thrombectomy in Large Vessel Occlusion Stroke: Safety and Early Efficacy from a Dose-Escalation Randomized Trial

By MedXY 09/11/2025

Adjunctive intra-arterial tenecteplase after successful reperfusion in anterior circulation large vessel occlusion stroke demonstrates an acceptable safety profile at low doses, supporting further investigation into its therapeutic potential.