Determinants of Serum Dexamethasone Levels During the 1-mg Overnight Dexamethasone Suppression Test: Clinical and Pharmacological Insights

Determinants of Serum Dexamethasone Levels During the 1-mg Overnight Dexamethasone Suppression Test: Clinical and Pharmacological Insights

This study investigates clinical and pharmacological factors influencing serum dexamethasone levels during the 1-mg overnight dexamethasone suppression test, revealing age and BMI as key determinants and highlighting the limited impact of renal function and concurrent medications after adjustment.
Longitudinal Changes in Cortisol Secretion and Cardiometabolic Outcomes in Benign Adrenal Incidentalomas: Insights from a Large Retrospective Cohort

Longitudinal Changes in Cortisol Secretion and Cardiometabolic Outcomes in Benign Adrenal Incidentalomas: Insights from a Large Retrospective Cohort

This study examines how temporal cortisol secretion changes in benign adrenal incidentalomas relate to long-term cardiometabolic outcomes and mortality, highlighting the significance of persistent mild autonomous cortisol secretion for hypertension management.
Intimacy, Intranasal Oxytocin, and Faster Wound Healing: A Randomized Trial Linking Touch, Sex, and Neuroendocrine Recovery

Intimacy, Intranasal Oxytocin, and Faster Wound Healing: A Randomized Trial Linking Touch, Sex, and Neuroendocrine Recovery

A double‑blind RCT in 160 healthy adults found that intranasal oxytocin combined with structured positive interaction and daily physical intimacy (affectionate touch, sex) was associated with reduced cortisol and modestly faster dermatologic wound healing, with caveats on robustness and generalizability.