chronic pain – Medxy AI

Predicting Opioid Use Disorder and Overdose Risk in Older Adults: Evaluating Prognostic Models

By MedXY 07/21/2026

This study develops and compares predictive models incorporating claims and patient-reported data to forecast time to first opioid use disorder (OUD) or overdose (OD) among older adults with chronic pain on opioids, identifying key risk factors for early intervention.

news Ophthalmology

Increased Risk of Dry Eye Disease in Patients with Chronic Pain Conditions: Insights from a Large Retrospective Cohort Study

By MedXY 07/20/2026

Chronic pain conditions significantly elevate the risk of developing dry eye disease, including cases requiring prescription therapy, emphasizing the need for integrated clinical assessment and management.

Anesthesiology Clinical Updates news Public Health

Patient-Centered Prescription Opioid Tapering: Evidence from a Multisite Randomized Clinical Trial and Complementary Digital Interventions

By MedXY 07/12/2026

A large RCT found that adding behavioral therapies to patient-centered opioid tapering did not improve taper success at 12 months, though CBT may reduce adverse effects; complementary digital support programs show feasibility but require further validation.

Anesthesiology Neurology news

The Hidden Driver of Chronic Pain: How Macrophages Fuel Neuropathic Symptoms

By MedXY 03/27/2026

Researchers using human stem cell models have discovered that macrophages actively amplify the electrical signals of damaged nerves, driving the spontaneous pain characteristic of neuropathy, offering a new target for non-opioid pain relief.

Internal Medicine Nephrology news

Beyond the Dialyzer: The Multidimensional Burden of Chronic Pain in Maintenance Hemodialysis Patients

By MedXY 02/03/2026

A cross-sectional analysis of the HOPE Consortium Trial reveals that chronic pain in hemodialysis patients is widespread, frequently musculoskeletal and neuropathic, and strongly associated with psychological and sociodemographic factors rather than dialysis-specific metrics.

news Psychiatry Public Health

Unlocking the Complexity of Co-Occurring Chronic Pain and Psychological Distress in Young Adults: Insights from Machine Learning and Explainable AI

By MedXY 10/24/2025

This study applies machine learning and explainable AI to identify factors associated with chronic pain, psychological distress, and their co-occurrence in Norwegian young adults, highlighting the importance of integrated approaches for early intervention.

OB/GYN & Women's Health Public Health

From Adolescence to Adulthood: The Lasting Impact of Dysmenorrhoea on Chronic Pain Risk

By MedXY 10/19/2025

A UK cohort study reveals that adolescent dysmenorrhoea increases the risk of chronic pain in adulthood, highlighting the need for early identification and management.

Clinical Updates Neurology news Specialties

Sleep Quality and Cognitive Performance in Chronic Primary Musculoskeletal Pain

By MedXY 08/16/2025

This study investigates the relationship between sleep quality and cognitive function in individuals with chronic primary musculoskeletal pain.

Clinical Updates news Orthopedics Specialties

Expanding Access to Chronic Pain Care: Telehealth and Online CBT-Based Interventions Show Promise

By MedXY 07/30/2025

Remote CBT-based interventions, delivered by telehealth or online modules, offer modest but significant improvements in pain and function for individuals with high-impact chronic pain, enhancing access to evidence-based care.