Digital multimodal lifestyle intervention in multiple sclerosis (MS) demonstrated sustained improvements in physical and psychological functioning up to 24 months.
Most significant behavioral changes and sustained benefits were observed in dietary adherence and body mass index, emphasizing the importance of nutrition.
Physical activity adherence did not show significant improvement, highlighting challenges in sustaining exercise behaviors in MS populations.
Findings underscore the complementary role of lifestyle strategies alongside disease-modifying therapies for long-term MS management.
