Post-Pandemic Firearm Acquisition and Household Exposure: Insights from the 2024 National Firearms Survey

Post-Pandemic Firearm Acquisition and Household Exposure: Insights from the 2024 National Firearms Survey

The 2024 National Firearms Survey reveals that 29.8 million US adults acquired firearms between 2021 and 2024. This trend introduced 11.2 million new owners, significantly increasing household exposure for millions of adults and children, raising critical public health concerns regarding violent death risks.
Cardiovascular Risk Scores Overestimate Mortality in Mexican Adults: The Urgent Need for Population-Specific Recalibration

Cardiovascular Risk Scores Overestimate Mortality in Mexican Adults: The Urgent Need for Population-Specific Recalibration

A prospective study of over 112,000 adults in Mexico City reveals that standard CVD risk scores consistently overestimate 10-year fatal risk. Recalibration of the Globorisk-fatal model significantly improves predictive accuracy, highlighting the need for population-specific tools in clinical practice.

Long-term Immunological and Clinical Outcomes of Monkeypox Virus Infection versus MVA-BN Vaccination: A 24-Month Longitudinal Cohort Analysis

This 24-month Belgian cohort study demonstrates that natural MPXV infection induces more durable and robust immunity than MVA-BN vaccination. While clinical symptoms mostly resolve within a year, persistent scarring remains common, and vaccine-induced immunity wanes significantly, highlighting the potential need for booster strategies.
Scaling Tobacco Cessation in HIV Care: National Quitlines as an Effective Alternative to Resource-Intensive Interventions

Scaling Tobacco Cessation in HIV Care: National Quitlines as an Effective Alternative to Resource-Intensive Interventions

A landmark pragmatic randomized controlled trial in Vietnam reveals that proactive Quitline referrals are as effective as nurse-led counseling and nicotine replacement therapy for smoking cessation among people living with HIV, offering a scalable model for low- and middle-income countries.
Beyond Monotherapy: Combined High-Intensity Circuit Training and Sleep Health Intervention Synergistically Enhances Sleep and Cardiometabolic Outcomes

Beyond Monotherapy: Combined High-Intensity Circuit Training and Sleep Health Intervention Synergistically Enhances Sleep and Cardiometabolic Outcomes

A randomized clinical trial demonstrates that combining high-intensity circuit training (HICT) with sleep health (SH) counseling significantly outperforms mono-interventions in improving sleep efficiency, reducing wakefulness, and enhancing cardiometabolic markers in sedentary young women.
Strategic Release of Wolbachia-Infected Mosquitoes Reduces Dengue Risk by Over 70% in Urban Singapore

Strategic Release of Wolbachia-Infected Mosquitoes Reduces Dengue Risk by Over 70% in Urban Singapore

A large-scale cluster-randomized trial in Singapore demonstrates that releasing male Aedes aegypti mosquitoes infected with the wAlbB Wolbachia strain significantly suppresses wild-type populations and reduces the incidence of symptomatic dengue virus infection by 71-72%, offering a transformative approach to urban vector control.
Standard Preventive Interventions for Vasovagal Reactions Fail to Show Benefit in Massive 1.4 Million Donor Trial

Standard Preventive Interventions for Vasovagal Reactions Fail to Show Benefit in Massive 1.4 Million Donor Trial

The STRIDES trial, the largest of its kind, demonstrates that isotonic drinks, extended rest, modified muscle tension, and psychosocial support do not significantly reduce vasovagal reactions in blood donors compared to existing UK standard practices, suggesting that current safety protocols may already be optimized.