Human versus Analogue Insulin for Youth with Type 1 Diabetes in Low-Resource Settings: Insights from the HumAn-1 Trial and Complementary Evidence

Human versus Analogue Insulin for Youth with Type 1 Diabetes in Low-Resource Settings: Insights from the HumAn-1 Trial and Complementary Evidence

The HumAn-1 trial found no significant differences between insulin glargine and human isophane insulin in hypoglycemia risk or glucose control in young T1D patients in low-resource settings, underscoring accessibility over insulin type in these contexts.
Efficacy and Safety of Mirtazapine in Treating Methamphetamine Use Disorder: Insights from a Phase 3 Randomized Clinical Trial

Efficacy and Safety of Mirtazapine in Treating Methamphetamine Use Disorder: Insights from a Phase 3 Randomized Clinical Trial

This randomized clinical trial evaluated mirtazapine's safety and efficacy for methamphetamine use disorder, revealing a modest but statistically significant reduction in methamphetamine use without unexpected adverse events, offering a promising pharmacotherapy option for this challenging condition.
Disparities in Postpartum Permanent Contraception Requests and Fulfillment: A Comparative Review Between Incarcerated and Community Populations

Disparities in Postpartum Permanent Contraception Requests and Fulfillment: A Comparative Review Between Incarcerated and Community Populations

This review synthesizes evidence on the lower prevalence and fulfillment rates of postpartum permanent contraception requests among incarcerated individuals compared to community counterparts, underscoring reproductive justice and health equity challenges.