Targeted Reduction of Sitting Time Versus Increased Sit-to-Stand Transitions: Effects on Blood Pressure and Glucose Regulation in Postmenopausal Women
Posted inCardiology Clinical Updates Diabetes & Endocrinology Family Medicine & Nutrition news OB/GYN & Women's Health Specialties

Targeted Reduction of Sitting Time Versus Increased Sit-to-Stand Transitions: Effects on Blood Pressure and Glucose Regulation in Postmenopausal Women

A 3-month randomized trial in overweight postmenopausal women found that increasing sit-to-stand transitions significantly reduces diastolic blood pressure, while reducing total sitting time alone does not improve blood pressure or glucoregulatory measures.
Impact of Maternal Trace Element Levels on Neonatal Growth Among Diabetic and Non-Diabetic Pregnancies
Posted inDiabetes & Endocrinology news OB/GYN & Women's Health Specialties

Impact of Maternal Trace Element Levels on Neonatal Growth Among Diabetic and Non-Diabetic Pregnancies

A case–control study reveals that elevated copper levels in diabetic pregnant women negatively affect newborn weight and head circumference, while chromium correlates positively with birth length. Smoking exposure adversely impacts infants’ weight, underscoring maternal trace element status and lifestyle as key determinants of neonatal outcomes.
Efficacy and Safety of Ecnoglutide, a cAMP-Biased GLP-1 Receptor Agonist, in Weight Management for Overweight and Obese Adults: Insights from a Phase 3 Multicentre Randomised Trial
Posted inDiabetes & Endocrinology Specialties

Efficacy and Safety of Ecnoglutide, a cAMP-Biased GLP-1 Receptor Agonist, in Weight Management for Overweight and Obese Adults: Insights from a Phase 3 Multicentre Randomised Trial

This review synthesizes evidence from a multicentre, phase 3 trial on ecnoglutide, demonstrating significant and sustained weight loss in overweight/obese adults without diabetes, with a favorable safety profile, supporting its clinical use in weight management.
Improving Sleep Quality through Cognitive Behavioural Therapy Alters Food Preferences in Adults with Overweight and Obesity
Posted inDiabetes & Endocrinology Gastroenterology Neurology news Specialties

Improving Sleep Quality through Cognitive Behavioural Therapy Alters Food Preferences in Adults with Overweight and Obesity

Cognitive behavioural therapy for insomnia enhances self-reported sleep quality and duration, reduces cravings for sweet and savoury foods, and shifts implicit food preferences in adults with overweight or obesity, though dietary intake changes remain uncertain.
Intermittent Fasting vs Low-Calorie Diet in Managing Metabolic-Associated Fatty Liver Disease: Comparative Effects on Inflammation, Lipids, Glycemic Control, and Liver Fibrosis
Posted inClinical Updates Diabetes & Endocrinology Gastroenterology news Specialties

Intermittent Fasting vs Low-Calorie Diet in Managing Metabolic-Associated Fatty Liver Disease: Comparative Effects on Inflammation, Lipids, Glycemic Control, and Liver Fibrosis

This RCT compares 16:8 intermittent fasting and low-calorie diets in MAFLD patients, revealing both improve liver enzymes and anthropometrics, but low-calorie diet shows superior reduction in liver steatosis, fibrosis, and triglycerides.
Association of Testosterone-Induced Neutrophil and Monocyte Elevation with Thromboembolic Risk: Insights from the TRAVERSE Trial
Posted inCardiology Diabetes & Endocrinology news Specialties

Association of Testosterone-Induced Neutrophil and Monocyte Elevation with Thromboembolic Risk: Insights from the TRAVERSE Trial

The TRAVERSE trial reveals that testosterone replacement therapy elevates neutrophil and monocyte counts in hypogonadal men, correlating with increased venous thromboembolism and cardiovascular event risk, underscoring the need to monitor these leukocytes during therapy.