Restoring Cortisol Rhythm May Be Key to Recovery After Cushing Syndrome

Highlights

Even after biochemical control of Cushing syndrome, many patients continue to experience anxiety, depression, impaired quality of life, and metabolic comorbidity.

In this cross-sectional study of 90 treated, biochemically controlled patients, normal late-night salivary cortisol was associated with better mood and better patient-reported quality of life than abnormal late-night salivary cortisol or long-term glucocorticoid replacement.

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