Highlight
- In recurrent Dupuytren contracture, surgical fasciectomy and collagenase injection yield comparable improvements in finger extension over 2 years.
- Re-recurrence rates were higher but not statistically different following collagenase injection compared to surgery.
- Surgical fasciectomy is associated with more severe adverse events, including nerve and artery injuries.
- Quality of life as measured by QuickDASH worsened transiently only in the surgical group early post-treatment.
