Acute Kidney Injury in Extremely Preterm Infants Predicts Higher Risk of Death or Neurodevelopmental Impairment at Two Years

Highlight

– In a secondary analysis of the PENUT randomized trial, AKI in extremely preterm infants (24–27 weeks’ gestation) was associated with higher adjusted odds of death or moderate to severe neurodevelopmental impairment at 22–26 months’ corrected age (AOR 1.53; 95% CI 1.07–2.18).

– Survivors with AKI had nearly doubled odds of cognitive delay (BSID-III cognitive score <85; AOR 1.94; 95% CI 1.25–2.99).

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