target trial emulation

Evaluating the Safety of Same-Day COVID-19 and Influenza Vaccination: Insights from a Large Veterans Affairs Target Trial Emulation

By MedXY 07/02/2026

A large U.S. Veterans Affairs study found no increased 90-day risk of adverse events after same-day COVID-19 and influenza vaccination compared to influenza vaccination alone, supporting the safety of coadministration with updated COVID-19 formulations.

news Ophthalmology

Dopamine-Enhancing Therapies in Age-Related Macular Degeneration: Assessing Risk Reduction for Neovascular Conversion

By MedXY 06/25/2026

This study evaluates the association of dopamine-enhancing drugs, especially levodopa, with lowered 3-year risk of progression from non-neovascular to neovascular AMD, offering promising insight into dopaminergic pathways in AMD management.

Neurology news Radiology

Intervention Lowers Long‑Term Hemorrhage Risk in Unruptured Brain AVMs: Evidence From a Nationwide Target‑Trial Emulation

By MedXY 11/19/2025

A large Chinese registry-based target-trial emulation found interventional therapy for unruptured brain AVMs reduced 5- and 10-year hemorrhage-free survival compared with conservative management, with benefits concentrated in low-grade, compact nidus lesions and driven mainly by microsurgery.