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Which Patients with Open-Angle Glaucoma Progress Faster? Key Prognostic Factors from a Cochrane Synthesis
Posted innews Ophthalmology

Which Patients with Open-Angle Glaucoma Progress Faster? Key Prognostic Factors from a Cochrane Synthesis

Posted by MedXY By MedXY 12/15/2025
A Cochrane review of 22 cohort studies (6,082 patients) found bilateral disease, disc haemorrhage, female sex, and active treatment have the most consistent associations with visual-field progression in open-angle glaucoma, but overall evidence quality is limited.
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Long-Term Survival Following Cytoreductive Surgery and HIPEC for Pseudomyxoma Peritonei: Insights from a 22-Year Single Institution Experience and Contemporary Evidence Synthesis
Posted inClinical Updates news Oncology

Long-Term Survival Following Cytoreductive Surgery and HIPEC for Pseudomyxoma Peritonei: Insights from a 22-Year Single Institution Experience and Contemporary Evidence Synthesis

Posted by MedXY By MedXY 11/06/2025
22-year single-center data confirm CRS and HIPEC as safe, effective for PMP, yielding 62% 5-year survival. Prognostic factors, optimized HIPEC regimens, and perioperative management impact outcomes and recurrence.
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Pre-Fitting Predictors of 2‑Year Hearing Aid Use in 284,175 US Veterans: When Patient Context Matters More Than Audiometry
Posted innews Otorhinolaryngology

Pre-Fitting Predictors of 2‑Year Hearing Aid Use in 284,175 US Veterans: When Patient Context Matters More Than Audiometry

Posted by MedXY By MedXY 11/04/2025
In 284,175 US veterans, nonmodifiable pre‑fitting factors—health comorbidity, mental status, prior hearing‑aid experience, age, race/ethnicity, and partnership—were independently associated with 2‑year hearing‑aid use persistence, beyond audiometric severity.
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Persistent High Mortality in Severe Alcohol-Associated Hepatitis: Insights from a Five-Decade Meta-Analysis
Posted inGastroenterology Internal Medicine news

Persistent High Mortality in Severe Alcohol-Associated Hepatitis: Insights from a Five-Decade Meta-Analysis

Posted by MedXY By MedXY 10/09/2025
This meta-analysis reveals that short-term mortality in severe alcohol-associated hepatitis remains high, with no significant improvement over the past four decades despite advances in care, underscoring the urgent need for better therapies and prognostic strategies.
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  • Epigenetic Regulation of Myocardial Inflammation: The Role of Macrophage PRMT9 and STAT1 Degradation in Acute Myocardial Infarction
  • Semaglutide Reduced Effort Discounting and Improved Motivation Signals in Major Depressive Disorder
  • Continuous Subphenotype Probabilities Expose High-Risk Patients Hidden Within “Hypoinflammatory” Acute Respiratory Failure
  • Earlier Mechanical Thrombectomy for Intermediate-Risk Pulmonary Embolism Improves Hemodynamics but Not In-Hospital Mortality
  • Ambient AI Scribes Reduced Emergency Department Documentation Time, but Early Adoption Was Limited and Highly Concentrated
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