High Versus Low Transvaginal Cerclage for Preventing Preterm Birth: Insights from the C-STICH Trial Secondary Analysis

High Versus Low Transvaginal Cerclage for Preventing Preterm Birth: Insights from the C-STICH Trial Secondary Analysis

This secondary analysis of the C-STICH trial compares pregnancy outcomes following high versus low vaginal cerclage in women at high risk of preterm birth, finding no significant difference in pregnancy loss but a modest benefit of high cerclage in prolonging gestation and reducing very early preterm births.
Increased Gestational Weight Gain and Adverse Pregnancy Outcomes After Stopping GLP‑1 Receptor Agonists Prior to or in Early Pregnancy

Increased Gestational Weight Gain and Adverse Pregnancy Outcomes After Stopping GLP‑1 Receptor Agonists Prior to or in Early Pregnancy

In a large retrospective cohort, women who discontinued GLP‑1 receptor agonists shortly before or during early pregnancy had greater gestational weight gain and higher risks of preterm birth, gestational diabetes, and hypertensive disorders compared with propensity‑matched unexposed pregnancies.
Nationwide Prevention Programme in Australia Associated with Lower Preterm and Early‑Term Singleton Births: National and Hospital‑Level Results

Nationwide Prevention Programme in Australia Associated with Lower Preterm and Early‑Term Singleton Births: National and Hospital‑Level Results

A multifaceted national preterm birth prevention programme in Australia was associated with a modest national decrease in late preterm births and, after a hospital collaborative, a substantial reduction in early‑term births in participating centres, without increasing preterm rates.