Postoperative Pain

Suzetrigine’s Role in Reducing Opioid Use After Head and Neck Surgery: A Retrospective Cohort Analysis

By MedXY 09/22/2026

This study associates adjunctive suzetrigine use with decreased postoperative opioid consumption in patients undergoing head and neck free flap or transoral robotic surgery, without increasing pain scores or adverse events.

Anesthesiology news OB/GYN & Women’s Health

Nonopioid vs Opioid Pain Management After Laparoscopic Hysterectomy: A Noninferiority Randomized Trial

By MedXY 08/06/2026

A recent randomized controlled trial demonstrates that nonopioid analgesia is noninferior to routine opioid prescribing for pain control after minimally invasive hysterectomy, with high patient satisfaction and markedly reduced opioid use.

news Otorhinolaryngology

Celecoxib Cuts Opioid Use Nearly in Half After Throat Surgery—Without Increasing Pain

By MedXY 04/02/2026

A retrospective cohort study of 80 patients undergoing tonsillectomy, adenoidectomy, or uvulopalatopharyngoplasty found that adding celecoxib to multimodal analgesia reduced mean opioid consumption by 44%, while maintaining comparable pain control across postoperative days 1, 5, and 10.

Anesthesiology news Orthopedics

Precision Medicine Fails to Improve Postoperative Pain: Insights from the CYP2D6-Guided Opioid Trial

By MedXY 02/23/2026

A randomized clinical trial demonstrates that while CYP2D6 genotyping significantly shifts opioid prescribing patterns for poor and intermediate metabolizers, it does not improve pain control or reduce opioid consumption within the context of modern multimodal postoperative care.

Anesthesiology General Surgery news OB/GYN & Women's Health Specialties

Quercetin as an Adjunct for Post-Cesarean Pain: Clinical Promise from a Randomized Controlled Trial

By MedXY 08/09/2025

Preoperative Quercetin significantly reduces post-cesarean pain and accelerates patient mobilization, offering a safe adjunct to current pain management protocols.