Major Abdominal Surgery

Optimizing Intraoperative Blood Pressure in Hypertensive High-Risk Patients: Insights from the HISTAP Trial

By MedXY 07/09/2026

In hypertensive high-risk patients undergoing major abdominal surgery, targeting an intraoperative mean arterial pressure ≥80 mmHg reduces postoperative organ dysfunction and acute kidney injury compared to the standard target of ≥65 mmHg.

Anesthesiology Critical Care news

Preventing Post‑Induction Hypotension With Low‑Dose Norepinephrine Reduces Postoperative Complications After Major Abdominal Surgery

By MedXY 11/06/2025

A single‑center RCT found that starting a titrated norepinephrine infusion at anesthesia induction reduced intraoperative hypotension and lowered 30‑day medico‑surgical complications compared with reactive ephedrine boluses in high‑risk abdominal surgery patients.

Anesthesiology General Surgery news Specialties

Intensive vs Conventional Intraoperative Blood Pressure Management: Insights from the BP-CARES Trial on Cardiovascular Outcomes After Major Abdominal Surgery

By MedXY 09/22/2025

The BP-CARES randomized trial found no cardiovascular benefit of intensive intraoperative blood pressure management (MAP ≥80 mm Hg) over conventional targets in high-risk major abdominal surgery patients.