glucose metabolism

Trogocytosis-Mediated CLDN18.2 Acquisition by CD8+ T Cells Impairs Anti-Tumor Immunity and Drives Pancreatic Cancer Progression

By MedXY 09/17/2026

This study reveals that CLDN18.2 acquired by CD8+ T cells through trogocytosis impairs their glucose metabolism and cytotoxic function, promoting pancreatic cancer progression and systemic immune senescence. Targeting this axis may enhance immunotherapy efficacy in PDAC.

Diabetes & Endocrinology news Pediatrics

Impact of Elexacaftor/Tezacaftor/Ivacaftor Therapy on Glucose Metabolism in Youths with Cystic Fibrosis: Insights from Continuous Glucose Monitoring

By MedXY 09/04/2026

This study demonstrates that initiation of elexacaftor/tezacaftor/ivacaftor (ETI) therapy in children and adolescents with cystic fibrosis improves continuous glucose monitoring (CGM) metrics, correlating with better clinical outcomes.

Diabetes & Endocrinology news

Mild Cold Exposure with Shivering Lowers 24-Hour Glucose Levels in Type 2 Diabetes: A Novel Adjunctive Therapy

By MedXY 07/22/2026

Acute mild cold exposure with shivering significantly reduces 24-hour glucose levels and improves glycemic profiles in individuals with type 2 diabetes, but not in prediabetic subjects, suggesting a potential non-pharmacological intervention for glucose control.

Clinical Updates Neurology news

Disentangling Cognitive Decline: The Interplay of White Matter Hyperintensities and Cortical Metabolism in Amyloid-Negative Patients

By MedXY 03/15/2026

This review synthesizes findings on how periventricular white matter hyperintensities (PWMHs) drive cognitive impairment in Aβ-negative individuals through distinct metabolic mediation and direct structural pathways, highlighting the clinical value of multi-modal PET/MRI imaging.

Diabetes & Endocrinology news OB/GYN & Women's Health Specialties

Evaluating Selenium Supplementation in Gestational Diabetes Mellitus: Insights from a Systematic Review and Meta-Analysis

By MedXY 10/12/2025

Selenium supplementation at 200 µg/d may reduce fasting plasma glucose and newborn hyperbilirubinemia risk in gestational diabetes without significantly altering lipid profiles, highlighting potential but limited benefits requiring further research.

Medical News news Oncology Specialties

Unmasking Brain Cancer’s Sugar Secret: How Glioblastoma Hijacks Glucose to Fuel Tumor Growth and Resist Therapy

By MedXY 09/04/2025

A groundbreaking Nature study reveals how glioblastoma reprograms glucose metabolism, exploiting environmental serine to accelerate growth and resist treatment, offering new metabolic targets for personalized therapies.

Cardiology Family Medicine & Nutrition news Specialties

Mediterranean Diet vs. Australian Guide to Healthy Eating: A Comparison on Body Composition and Glucose Metabolism

By MedXY 08/11/2025

This study compares the effects of the Mediterranean diet and the Australian Guide to Healthy Eating (AGHE) on body composition and glucose metabolism, revealing significant benefits of the Mediterranean diet.