Evaluating Selenium Supplementation in Gestational Diabetes Mellitus: Insights from a Systematic Review and Meta-Analysis

Highlight

  • Selenium supplementation at 200 µg/day significantly reduces fasting plasma glucose levels in women with gestational diabetes mellitus (GDM).
  • Reduced incidence of newborn hyperbilirubinemia was observed with selenium supplementation.
  • Selenium did not significantly impact insulin resistance as measured by HOMA-IR or lipid profiles including total cholesterol, triglycerides, LDL-C, and HDL-C.
  • Current evidence draws from a limited number of randomized controlled trials, warranting cautious interpretation and need for further validation.

Study Background

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