cardiovascular risk – Page 3

Molecular Mutations and Cardiovascular Risks Shape Prognosis in Triple-Negative Essential Thrombocythemia

By MedXY 07/15/2026

This study reveals that specific gene mutations and cardiovascular risk factors significantly influence prognosis and thrombotic risk in triple-negative essential thrombocythemia, highlighting the importance of molecular profiling for personalized treatment.

Cardiology news Public Health

Wine Consumption, Mediterranean Diet, and Cardiovascular Risk in Two Spanish Cohorts

By MedXY 07/14/2026

This study from two Spanish cohorts explores how moderate wine consumption within a Mediterranean diet impacts cardiovascular disease and mortality, suggesting modest benefits but advising cautious interpretation.

Cardiology news

Assessing Cardiovascular Risk in First-Degree Relatives of Individuals with Elevated Lipoprotein(a): Insights from a Swedish Cohort Study

By MedXY 07/12/2026

A cohort study demonstrates increased major cardiovascular event risk in first-degree relatives of individuals with high plasma lipoprotein(a), supporting cascade screening for targeted prevention.

Cardiology news

Unveiling the Natural History of Asymptomatic Mild Hypertrophic Cardiomyopathy: Insights from the SHaRe Registry

By MedXY 07/09/2026

This study reveals that 21% of asymptomatic patients with mild HCM develop major adverse cardiovascular events over 7 years, highlighting key predictors such as age, symptom progression, and cardiac remodeling markers that inform management and future therapies.

Cardiology news

Obicetrapib’s Impact on Lipoprotein(a) in High Cardiovascular Risk Patients: A Comprehensive Pooled Analysis

By MedXY 07/07/2026

Obicetrapib significantly lowers lipoprotein(a), LDL cholesterol, and apolipoprotein B in high cardiovascular risk patients, offering a promising addition to lipid-lowering therapies, especially for patients with mild to moderate Lp(a) elevation.

Clinical Updates news Respiratory

Modified Sleep Apnea Severity Index and Cardiovascular Risk in CPAP-Intolerant OSA Patients: A Clinical Evidence Review

By MedXY 07/02/2026

This review synthesizes current evidence on the modified sleep apnea severity index (mSASI) as a composite metric integrating clinical and sleep study factors to predict cardiovascular risk in CPAP-intolerant OSA patients undergoing surgery.

Cardiology Internal Medicine news

Oral NLRP3 Inhibition With Ruvonoflast Produces Rapid, Reversible Suppression of Residual Inflammation in Adults at High Cardiovascular Risk

By MedXY 06/10/2026

In a Phase 1b placebo-controlled trial, ruvonoflast markedly reduced hsCRP, IL-6, and fibrinogen over 28 days in adults with obesity, elevated hsCRP, and cardiometabolic risk, supporting further evaluation of oral NLRP3 inhibition in atherosclerotic prevention.

Cardiology news Public Health

The Prognostic Value of Serum Interleukin-6 Concentrations for 9 Cardiovascular and Mortality Outcomes

By MedXY 06/10/2026

Higher blood IL-6 levels were strongly linked to nine cardiovascular and mortality outcomes in nearly 60,000 adults, supporting IL-6 as an important inflammatory marker and potential prevention target.

Cardiology Diabetes & Endocrinology news

Precision Prescribing of SGLT2 Inhibitors in People With Type 2 Diabetes for Primary Prevention of Heart Failure: Model Development and Validation Study

By MedXY 06/10/2026

The SABRE model estimates which people with type 2 diabetes may benefit most from SGLT2 inhibitors to prevent heart failure before it develops.

Cardiology Internal Medicine news

Higher Interleukin-6 Levels Predict Broad Cardiovascular Risk and Mortality Across Diverse Cohorts

By MedXY 05/31/2026

A pooled analysis of 59,396 participants found that higher serum IL-6 concentrations independently predicted nine cardiovascular and mortality outcomes, with consistent associations across key clinical subgroups.

Clinical Updates news

Addressing the Equity Gap in Familial Hypercholesterolemia: Comparative Insights into African and European Ancestry Populations

By MedXY 05/31/2026

This review analyzes evidence comparing Familial Hypercholesterolemia (FH) across ancestries, highlighting that while pathogenic variant prevalence is similar, African ancestry individuals face higher LDL-C burdens and significant risks from variants currently classified as uncertain.

Cardiology Neurology news

Prior Myocardial Infarction and Cognitive Decline: Insights from the REGARDS Cohort

By MedXY 05/16/2026

In the REGARDS cohort, prior myocardial infarction, including silent MI, was linked to faster long-term cognitive decline, suggesting heart attack history may help identify people at risk for future cognitive impairment.

Cardiology Clinical Updates news

Beyond Neuronal Injury: Serum Neurofilament Light Chain as a Prognostic Biomarker for Cardiovascular Outcomes in Atrial Fibrillation

By MedXY 05/15/2026

This review analyzes the landmark SWISS-AF study, demonstrating that serum neurofilament light chain (sNfL), traditionally a marker of neuronal damage, is a potent independent predictor of major vascular events, heart failure, and mortality in patients with atrial fibrillation.

Cardiology news

Laroprovstat, the First Oral Small-Molecule PCSK9 Inhibitor for Hypercholesterolemia: Results From a Phase 1 Trial

By MedXY 05/15/2026

Laroprovstat, an investigational oral PCSK9 inhibitor, was well tolerated and produced substantial LDL cholesterol reductions, especially when combined with rosuvastatin, supporting further development for hypercholesterolemia.

Cardiology news Respiratory

A GOLD Science Committee Perspective on Exacerbations and Cardiovascular Risk In COPD

By MedXY 05/11/2026

COPD exacerbations significantly increase cardiovascular risk for months. This article examines the link between COPD and heart disease, emphasizing proactive screening during flare-ups and evidence-based prevention strategies to improve survival rates.

Cardiology HIV/AIDS Infectious Diseases news

Elevated Heart Failure Risk in People With HIV: Insights from the REPRIEVE Trial

By MedXY 04/29/2026

The REPRIEVE trial reveals higher heart failure incidence in people with HIV, particularly among women, Black participants in high-income regions, and those with hypertension or obesity. Traditional risk factors, not HIV-specific markers, were key predictors.

Cardiology Diabetes & Endocrinology news OB/GYN & Women's Health

Prolonged TSH Suppression in Postmenopausal Thyroid Cancer Patients Linked to Worse Cardiovascular and Quality-of-Life Outcomes

By MedXY 04/28/2026

Study finds long-term TSH suppression in postmenopausal women with thyroid cancer correlates with poorer cardiovascular health, reduced quality of life, and increased osteoporosis risk compared to controls.

Clinical Updates Diabetes & Endocrinology news Ophthalmology

Glucagon-Like Peptide-1 Receptor Agonists and Vascular Protection: Mitigating Systemic and Ocular Risks in High-Risk Type 2 Diabetes

By MedXY 04/27/2026

A large-scale cohort study demonstrates that GLP-1 RAs significantly reduce macrovascular and microvascular complications, including proliferative retinopathy and retinal vein occlusion, in patients with pre-existing diabetic retinopathy.

Cardiology news

44% of Women with HDP Develop Chronic Hypertension Within 10 Years: Missed Opportunities in Postpartum Care

By MedXY 04/23/2026

A French cohort study reveals 44% of women receiving postpartum antihypertensives after HDP develop chronic hypertension within 10 years, signaling urgent gaps in long-term cardiovascular risk monitoring.

Cardiology Neurology news

Even ‘Elevated’ Blood Pressure Raises Dementia Risk: Insights from 2.8 Million Adults Over 8 Years

By MedXY 04/15/2026

A landmark South Korean study of 2.8 million adults reveals that both elevated blood pressure and hypertension significantly increase dementia risk, particularly vascular dementia, with stronger effects observed in midlife adults and women. The findings validate the 2024 ESC blood pressure classification system.